Atp6v1b2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
MGI:109618

26 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atp6v1b2^em1Pcamp/Atp6v1b2⁺ C57BL/6N-Atp6v1b2^em1Pcamp	abnormal birth body size	J:342781
	normal behavior/neurological phenotype	J:342781
	normal embryo phenotype	J:342781
	increased susceptibility to pharmacologically induced seizures	J:342781
	normal mortality/aging	J:342781
Atp6v1b2^em1Pcamp/Atp6v1b2^em1Pcamp C57BL/6N-Atp6v1b2^em1Pcamp	abnormal birth body size	J:342781
	normal behavior/neurological phenotype	J:342781
	decreased thigmotaxis	J:342781
	normal embryo phenotype	J:342781
	environmentally induced seizures	J:342781
	normal hearing/vestibular/ear phenotype	J:342781
	normal homeostasis/metabolism phenotype	J:342781
	increased locomotor activity	J:342781
	increased susceptibility to pharmacologically induced seizures	J:342781
	normal mortality/aging	J:342781
	normal nervous system phenotype	J:342781
Atp6v1b2^{tm1b(KOMP)Wtsi}/Atp6v1b2⁺ C57BL/6N-Atp6v1b2^{tm1b(KOMP)Wtsi}/Tcp	decreased hemoglobin content	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased mean corpuscular volume	J:211773
	increased circulating alkaline phosphatase level	J:211773
	small adrenal glands	J:211773
	small lymph nodes	J:211773
Atp6v1b2^{tm1b(KOMP)Wtsi}/Atp6v1b2^{tm1b(KOMP)Wtsi} C57BL/6N-Atp6v1b2^{tm1b(KOMP)Wtsi}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Atp6v1b2^tm1Yoyu/Atp6v1b2⁺ involves: C57BL/6	normal behavior/neurological phenotype	J:278514
	normal growth/size/body region phenotype	J:278514
	normal hearing/vestibular/ear phenotype	J:278514
	impaired passive avoidance behavior	J:278514
	impaired short-term object recognition memory	J:278514
Atp6v1b2^tm1Yoyu/Atp6v1b2^tm1Yoyu involves: C57BL/6	abnormal hippocampus CA1 region morphology	J:278514
	normal behavior/neurological phenotype	J:278514
	environmentally induced seizures	J:278514
	normal hearing/vestibular/ear phenotype	J:278514
	impaired passive avoidance behavior	J:278514
	impaired short-term object recognition memory	J:278514
	slow postnatal weight gain	J:278514

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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