Mesp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mesp2
mesoderm posterior 2
MGI:1096325

49 phenotypes from 12 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mesp1/Mesp2^tm1Ysa/Mesp1/Mesp2^tm1Ysa involves: C57BL/6 * CBA * ICR	abnormal blood vessel morphology	J:62984
	abnormal ectoderm development	J:62984
	abnormal endoderm development	J:62984
	abnormal gastrulation	J:62984
	abnormal mesoderm development	J:62984
	abnormal primitive streak formation	J:62984
	absent heart	J:62984
	absent mesoderm	J:62984
	absent paraxial mesoderm	J:62984
	absent somites	J:62984
	decreased embryo size	J:62984
	embryonic lethality during organogenesis, complete penetrance	J:62984
Mesp2^tm1Ysa/Mesp2^tm1Ysa either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * ICR)	abnormal axon extension	J:42014
	abnormal dermomyotome development	J:42014
	abnormal paraxial mesoderm morphology	J:42014
	abnormal rostral-caudal patterning of the somites	J:42014
	abnormal sclerotome morphology	J:42014
	abnormal somite border morphology	J:42014
	abnormal vertebrae morphology	J:42014
	abnormal vertebral lamina morphology	J:42014
	absent intervertebral disk	J:42014
	cervical vertebral fusion	J:42014
	decreased body length	J:42014
	delayed somite formation	J:42014
	fused dorsal root ganglion	J:42014
	fusion of vertebral arches	J:42014
	incomplete somite formation	J:42014
	normal integument phenotype	J:42014
	lumbar vertebral fusion	J:42014
	normal muscle phenotype	J:42014
	neonatal lethality, complete penetrance	J:42014
	rib fusion	J:42014
	spina bifida	J:42014
	vertebral fusion	J:42014
	vestigial tail	J:42014
Mesp2^tm1Ysa/Mesp2^tm1Ysa involves: C57BL/6 * CBA	abnormal somite border morphology	J:75945
	abnormal somite development	J:75945
	absent somites	J:75945
Mesp2^tm4Ysa/Mesp2^tm4Ysa involves: C57BL/6 * CBA	abnormal somite development	J:78989
	abnormal vertebral lamina morphology	J:78989
	abnormal vertebral pedicle morphology	J:78989
	abnormal vertebral transverse process morphology	J:78989
Mesp2^tm8Ysa/Mesp2^tm8Ysa involves: C57BL/6 * CBA * ICR	rib fusion	J:119678
Mesp2^tm9Ysa/Mesp2^tm9Ysa involves: C57BL/6 * CBA * ICR	rib fusion	J:119678
Mesp2^tm10Ysa/Mesp2^tm10Ysa involves: C57BL/6 * CBA * ICR	abnormal cervical vertebrae morphology	J:119678
	abnormal rib morphology	J:119678
	abnormal thoracic vertebrae morphology	J:119678
	abnormal vertebrae development	J:119678
	abnormal vertebrae morphology	J:119678
Mesp2^tm10Ysa/Mesp2^tm11Ysa involves: C57BL/6 * CBA * ICR	abnormal vertebrae morphology	J:119678
Mesp2^tm10Ysa/Mesp2^tm11Ysa involves: C57BL/6 * CBA * ICR	fusion of vertebral arches	J:119678
Mesp2^tm11Ysa/Mesp2^tm11Ysa involves: C57BL/6 * CBA * ICR	abnormal cervical vertebrae morphology	J:119678
	abnormal rib morphology	J:119678
	abnormal sacral vertebrae morphology	J:119678
	abnormal somite development	J:119678
	abnormal thoracic vertebrae morphology	J:119678
	abnormal vertebrae morphology	J:119678
	fusion of vertebral arches	J:119678
Mesp2^tm12Ysa/Mesp2^tm12Ysa involves: C57BL/6 * CBA * ICR	abnormal skeleton morphology	J:141112
	abnormal vertebrae morphology	J:141112
	perinatal lethality	J:141112
	rib fusion	J:141112
	short vertebral column	J:141112
Mesp2^{tm13(cre/Esr1*)Ysa}/Mesp2⁺ involves: C57BL/6J	abnormal vertebrae morphology	J:186213
Mesp2^{tm13(cre/Esr1*)Ysa}/Mesp2⁺ Not Specified	abnormal vertebrae morphology	J:186213
Mesp2^{tm13(cre/Esr1)Ysa}/Mesp2^{tm13(cre/Esr1)Ysa} involves: C57BL/6 * SJL	abnormal somite development	J:122532
Mesp2^{tm13.1(cre/Esr1)Ysa}/Mesp2^{tm13.1(cre/Esr1)Ysa} involves: C57BL/6 * SJL	abnormal somite border morphology	J:122532
	abnormal somite development	J:122532
	incomplete somite formation	J:122532
Mesp2^{tm13.1(cre/Esr1)Ysa}/Mesp2^{tm13.1(cre/Esr1)Ysa} Not Specified	abnormal rostral-caudal patterning of the somites	J:167045
	abnormal somite development	J:167045
	abnormal vertebrae morphology	J:141112
	decreased body length	J:167045
	fusion of vertebral arches	J:167045
	rib fusion	J:141112, J:167045
	short tail	J:167045
	short vertebral column	J:141112
Mesp2^tm14Ysa/Mesp2^tm14Ysa involves: C57BL/6 * CBA * ICR	normal skeleton phenotype	J:141112
Mesp2^tm18Ysa/Mesp2^tm18Ysa involves: C57BL/6 * CBA * ICR	no abnormal phenotype detected	J:141112

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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