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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adam10tm1Beni/Adam10tm1Beni
Adam17tm1.1Srj/Adam17tm1.1Srj
Tg(Pf4-icre)Q3Rsko/0
involves: 129/Sv * 129S/SvEv * C57BL/6 		abnormal platelet physiology J:165863
preweaning lethality, incomplete penetrance J:165863
Adam12tm1Asf/Adam12tm1Asf
Adam15tm1Bbl/Adam15tm1Bbl
Adam17tm1Imx/Adam17tm1Imx
Adam9tm1Bbl/Adam9tm1Bbl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal aortic valve morphology J:88801
abnormal mitral valve morphology J:88801
abnormal pulmonary valve morphology J:88801
abnormal tricuspid valve morphology J:88801
eyelids open at birth J:88801
neonatal lethality J:88801
thick aortic valve J:88801
thick mitral valve J:88801
thick pulmonary valve J:88801
thick tricuspid valve J:88801
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il17atm1Yiw/Il17atm1Yiw
Sox9tm3(cre)Crm/Sox9+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL 		dermatitis J:229771
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il23atm1Dnax/Il23atm1Dnax
Sox9tm3(cre)Crm/Sox9+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL 		dermatitis J:229771
Adam17tm1Imx/Adam17tm1Imx
Adam19Gt(Betageo)1Bbl/Adam19Gt(Betageo)1Bbl
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		abnormal myocardium layer morphology J:99649
absent myocardial trabeculae J:99649
lethality throughout fetal growth and development, complete penetrance J:99649
thin ventricular wall J:99649
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory