Terf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Terf1
telomeric repeat binding factor 1
MGI:109634

31 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Terf1^tm1.1Blas/Terf1^tm1.1Blas involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal chromosome morphology	J:152077
	abnormal telomere length	J:152077
	decreased cell proliferation	J:152077
	early cellular replicative senescence	J:152077
Terf1^tm1.1Blas/Terf1^tm1.1Blas Tg(KRT5-cre)1Tak/0 involves: 129 * C3H * C57BL/6 * SJL	abnormal chromosome morphology	J:152077
	abnormal esophageal epithelium morphology	J:152077
	abnormal esophagus morphology	J:152077
	abnormal filiform papillae morphology	J:152077
	abnormal keratinocyte physiology	J:152077
	abnormal palate morphology	J:152077
	abnormal skin development	J:152077
	abnormal skin morphology	J:152077
	abnormal skin physiology	J:152077
	abnormal stomach epithelium morphology	J:152077
	abnormal telomere length	J:152077
	abnormal tongue epithelium morphology	J:152077
	absent hair follicles	J:152077
	absent sebaceous gland	J:152077
	decreased body weight	J:152077
	epidermal hyperplasia	J:152077
	hyperkeratosis	J:152077
	impaired skin barrier function	J:152077
	increased skin pigmentation	J:152077
	orthokeratosis	J:152077
	perinatal lethality, incomplete penetrance	J:152077
	postnatal growth retardation	J:152077
	skin inflammation	J:152077
Terf1^tm1Tdl/Terf1⁺ involves: 129S2/SvPas	no abnormal phenotype detected	J:85440
Terf1^tm1Tdl/Terf1^tm1Tdl involves: 129S2/SvPas	abnormal ectoplacental cone morphology	J:85440
	abnormal extraembryonic tissue morphology	J:85440
	abnormal inner cell mass apoptosis	J:85440
	absent inner cell mass proliferation	J:85440
	embryonic lethality between implantation and somite formation, complete penetrance	J:85440
Terf1^tm2.1Tdl/Terf1^tm2.1Tdl involves: 129P2/OlaHsd * C57BL/6	early cellular replicative senescence	J:157331

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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