E2f2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

E2f2
E2F transcription factor 2
MGI:1096341

24 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
E2f2^tm1Zubi/E2f2^tm1Zubi involves: 129S1/Sv * C57BL/6	abnormal cell death	J:75726
	abnormal cell physiology	J:75726
	abnormal immune system morphology	J:76318
	abnormal immune system physiology	J:76318
	abnormal skin morphology	J:76318
	abnormal spleen white pulp morphology	J:76318
	abnormal T cell differentiation	J:76318
	abnormal T cell subpopulation ratio	J:76318
	enlarged spleen	J:76318
	glomerulonephritis	J:76318
	increased anti-double stranded DNA antibody level	J:76318
	increased inflammatory response	J:76318
	increased memory T cell number	J:76318
	increased renal glomerulus basement membrane thickness	J:76318
	increased spleen weight	J:76318
	increased susceptibility to autoimmune disorder	J:76318
	increased T cell proliferation	J:76318
	liver inflammation	J:76318
	lung inflammation	J:76318
	premature death	J:76318
	progressive hair loss	J:76318
	reddish skin	J:76318
	renal glomerular immunoglobulin deposits	J:76318
	renal glomerulus hypertrophy	J:76318

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24