E2f2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

E2f2
E2F transcription factor 2
MGI:1096341

24 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
E2f2^tm1Zubi/E2f2^tm1Zubi involves: 129S1/Sv * C57BL/6	abnormal cell death	J:75726
	abnormal cell physiology	J:75726
	abnormal immune system morphology	J:76318
	abnormal immune system physiology	J:76318
	abnormal skin morphology	J:76318
	abnormal spleen white pulp morphology	J:76318
	abnormal T cell differentiation	J:76318
	abnormal T cell subpopulation ratio	J:76318
	enlarged spleen	J:76318
	glomerulonephritis	J:76318
	increased anti-double stranded DNA antibody level	J:76318
	increased inflammatory response	J:76318
	increased memory T cell number	J:76318
	increased renal glomerulus basement membrane thickness	J:76318
	increased spleen weight	J:76318
	increased susceptibility to autoimmune disorder	J:76318
	increased T cell proliferation	J:76318
	liver inflammation	J:76318
	lung inflammation	J:76318
	premature death	J:76318
	progressive hair loss	J:76318
	reddish skin	J:76318
	renal glomerular immunoglobulin deposits	J:76318
	renal glomerulus hypertrophy	J:76318

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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