Rhoa Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rhoa
ras homolog family member A
MGI:1096342

20 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rhoa^tm1.1Tpal/Rhoa⁺ Tg(Cd4-cre/ERT2)11Gnri/0 involves: C57BL/6	increased regulatory T cell number	J:257764
	increased T cell proliferation	J:257764
	increased T follicular helper cell number	J:257764
Rhoa^tm1Csab/Rhoa^tm1Csab Not Specified	no abnormal phenotype detected	J:204459
Rhoa^tm1Csab/Rhoa^tm1Csab Tg(Pf4-icre)Q3Rsko/0 involves: C57BL/6	increased mean platelet volume	J:204459
	thrombocytopenia	J:204459
Rhoa^tm1Jrel/Rhoa^tm1Jrel Tg(Pou3f4-cre)32Cren/0 involves: CD-1	abnormal neural tube ventricular layer morphology	J:171199
	abnormal neuronal precursor proliferation	J:171199
	embryonic lethality, complete penetrance	J:171199
	increased spinal cord apoptosis	J:171199
	normal nervous system phenotype	J:171199
	premature neuronal precursor differentiation	J:171199
Rhoa^tm1Yuyo/Rhoa^tm1Yuyo Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd	abnormal brain development	J:172044
	exencephaly	J:172044
	increased neuronal precursor cell number	J:172044
Rhoa^tm1Yuyo/Rhoa^tm1Yuyo H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: C57BL/6J * CBA/J	abnormal brain morphology	J:172044
	abnormal midbrain development	J:172044
	abnormal midbrain morphology	J:172044
	abnormal neuron proliferation	J:172044
	exencephaly	J:172044
	increased midbrain size	J:172044
	increased neuronal precursor cell number	J:172044

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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