Gckr Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gckr
glucokinase regulatory protein
MGI:1096345

12 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gckr^em1(IMPC)H/Gckr^em1(IMPC)H C57BL/6NTac-Gckr^em1(IMPC)H/H	impaired glucose tolerance	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating creatinine level	J:211773
Gckr^tm1Bms/Gckr^tm1Bms involves: 129S1/Sv * C57BL/6	abnormal glucose homeostasis	J:58949
	increased circulating glucose level	J:58949
	increased circulating insulin level	J:58949
	insulin resistance	J:58949
Gckr^tm1Bms/Gckr^tm1Bms involves: 129S1/Sv * ICR	abnormal enzyme/coenzyme level	J:58949
	abnormal glucose homeostasis	J:58949
	decreased glucokinase activity	J:58949
	decreased liver glycogen level	J:58949
	normal homeostasis/metabolism phenotype	J:58949
	impaired glucose tolerance	J:58949
Gckr^tm1Jfg/Gckr^tm1Jfg involves: 129S/SvEv * C57BL/6J	abnormal enzyme/coenzyme level	J:61183
	decreased circulating insulin level	J:61183
	decreased glucokinase activity	J:61183
	impaired glucose tolerance	J:61183

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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