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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		S1pr1
sphingosine-1-phosphate receptor 1
MGI:1096355
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
S1pr1tm2Rlp/S1pr1tm2Rlp
Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129S6/SvEvTac * 129X1/SvJ 		abnormal aorta morphology J:189010
abnormal retina vasculature morphology J:189010
S1pr1tm1Rlp/S1pr1tm1Rlp
S1pr2tm1Rlp/S1pr2tm1Rlp
involves: 129S6/SvEvTac * C57BL/6 		abnormal angiogenesis J:106055
embryonic lethality during organogenesis, complete penetrance J:106055
hemorrhage J:106055
S1pr1tm1Rlp/S1pr1tm1Rlp
S1pr3tm1Rlp/S1pr3tm1Rlp
involves: 129S6/SvEvTac * C57BL/6 		abnormal limb morphology J:106055
embryonic lethality during organogenesis, complete penetrance J:106055
hemorrhage J:106055
S1pr1tm1Rlp/S1pr1tm1Rlp
S1pr3tm1Rlp/S1pr3tm1Rlp
S1pr2tm1Rlp/S1pr2tm1Rlp
involves: 129S6/SvEvTac * C57BL/6 		abnormal angiogenesis J:106055
embryonic lethality during organogenesis, complete penetrance J:106055
hemorrhage J:106055
S1pr1tm3.1(tTA,-Arrb2)Rlp/S1pr1+
Tg(tetO-HIST1H2BJ/GFP)47Efu/0
involves: 129S6/SvEvTac * C57BL/6 * CD-1 * FVB/N 		normal immune system phenotype J:212772
normal mortality/aging J:212772
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory