Nrxn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrxn2
neurexin II
MGI:1096362

20 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nrxn2^em1(IMPC)H/Nrxn2^em1(IMPC)H C57BL/6NTac-Nrxn2^em1(IMPC)H/H	abnormal gait	J:211773
	decreased locomotor activity	J:211773
	enlarged heart	J:211773
	hyperactivity	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating total protein level	J:211773
	increased circulating triglyceride level	J:211773
	increased lean body mass	J:211773
	tremors	J:211773
	trunk curl	J:211773
Nrxn2^tm1Sud/Nrxn2^tm1Sud involves: 129 * C57BL/6 * C57BL/6J * C57BL/6NClr	abnormal response to novel object	J:220076
	abnormal social investigation	J:220076
	increased anxiety-related response	J:220076
	increased vertical activity	J:220076
	normal nervous system phenotype	J:220076
Nrxn2^tm2Sud/Nrxn2^tm2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:101977
Nrxn2^tm3Sud/Nrxn2^tm3Sud involves: 129 * C57BL/6	abnormal inhibitory postsynaptic currents	J:142107
	decreased body weight	J:142107
	postnatal lethality	J:142107
Nrxn2^tm4Sud/Nrxn2^tm4Sud involves: C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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