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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bmal1
basic helix-loop-helix ARNT like 1
MGI:1096381
162 phenotypes from 10 alleles in 17 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmal1em1Bwu/Bmal1em1Bwu
C57BL/6-Bmal1em1Bwu 		abnormal intestine physiology J:340220
abnormal macrophage physiology J:340220
Bmal1tm1.1Ljm/Bmal1tm1.1Ljm
Tg(Mylk-cre)1Ljm/0
involves: C57BL/6 		abnormal parturition J:188253
delayed parturition J:188253
early parturition J:188253
normal homeostasis/metabolism phenotype J:188253
Bmal1tm1.1Ljm/Bmal1tm1.1Ljm
Tmem163Tg(ACTB-cre)2Mrt/0
involves: C57BL/6 * FVB/N 		abnormal circadian behavior J:188253
decreased locomotor activity J:188253
Bmal1tm1.1Shbi/Bmal1tm1.1Shbi
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: C57BL/6 * C57BL/6J * DBA 		normal behavior/neurological phenotype J:177865
normal liver/biliary system phenotype J:177865
Bmal1tm1.1Shbi/Bmal1tm1.1Shbi
Tg(Ckmm-cre)5Khn/0
involves: C57BL/6J * FVB 		normal behavior/neurological phenotype J:177865
normal muscle phenotype J:177865
Bmal1tm1.1Weit/Bmal1tm1.1Weit
involves: 129S4/SvJae * BALB/cJ 		abnormal circadian behavior J:124157
Bmal1tm1.2Shbi/Bmal1tm1.2Shbi
involves: C57BL/6J 		abnormal enzyme/coenzyme activity J:347048
abnormal gluconeogenesis J:177865
abnormal glucose homeostasis J:177865
abnormal lipid level J:177865
abnormal locomotor circadian rhythm J:177865
normal behavior/neurological phenotype J:177865
decreased body weight J:177865
decreased circulating HDL cholesterol level J:177865
decreased circulating insulin level J:177865
decreased circulating VLDL triglyceride level J:177865
decreased insulin secretion J:177865
decreased susceptibility to diet-induced obesity J:177865
decreased total body fat amount J:177865
decreased white fat cell size J:177865
enlarged pancreatic islets J:177865
normal homeostasis/metabolism phenotype J:177865
hyperglycemia J:177865
impaired glucose tolerance J:177865
increased circulating cholesterol level J:177865
increased circulating free fatty acids level J:177865
increased circulating HDL cholesterol level J:177865
increased circulating LDL cholesterol level J:177865
increased circulating triglyceride level J:177865
increased circulating VLDL cholesterol level J:177865
increased liver triglyceride level J:177865
increased respiratory quotient J:177865
increased sebum secretion J:177865
increased skeletal muscle triglyceride level J:177865
increased susceptibility to diet-induced hepatic steatosis J:177865
Meibomian gland atrophy J:347048
Bmal1tm1Bra/Bmal1+
involves: 129 * C57BL/6 		delayed circadian behavior phase J:177916
Bmal1tm1Bra/Bmal1tm1Bra
B6.129-Bmal1tm1Bra 		abnormal circadian behavior J:125921
abnormal circadian regulation of heart rate J:125921
abnormal circadian regulation of systemic arterial blood pressure J:125921
abnormal circulating adrenaline level J:125921
abnormal circulating protein level J:191844
abnormal cornea morphology J:110697
abnormal cornea stroma morphology J:110697
abnormal costal cartilage morphology J:97108
abnormal gait J:97108
abnormal knee joint morphology J:97108
abnormal lens fiber morphology J:110697
abnormal lens morphology J:110697
abnormal ligament morphology J:97108
abnormal metabolism J:110697
abnormal nitric oxide homeostasis J:191844
abnormal posture J:97108
abnormal rib morphology J:97108
abnormal tail movements J:97108
abnormal thoracic cage morphology J:97108
abnormal vascular smooth muscle physiology J:191844
abnormal venous thrombosis J:191844
abnormal vertebral column morphology J:97108
calcified calcaneal tendon J:97108, J:116189
calcified intervertebral disk J:97108
calcified joint J:97108
calcified tendon J:97108
cataract J:110697
cornea epithelium hyperplasia J:110697
cornea vascularization J:110697
decreased abdominal adipose tissue amount J:110697
decreased basophil cell number J:191844
decreased body size J:110697
decreased body weight J:97108, J:116189
decreased circulating adrenaline level J:125921
decreased circulating noradrenaline level J:125921
decreased heart rate J:125921
decreased heart weight J:110697
decreased kidney weight J:110697
decreased leukocyte cell number J:110697
decreased lung weight J:110697
decreased lymphocyte cell number J:110697
decreased mean systemic arterial blood pressure J:125921
decreased muscle weight J:110697
decreased prothrombin time J:191844
decreased spleen weight J:110697
decreased subcutaneous adipose tissue amount J:110697
decreased testis weight J:110697
decreased total body fat amount J:110697
decreased vasodilation J:191844
dehydration J:97108
ectopic bone J:97108
fused joints J:97108
normal hematopoietic system phenotype J:110697
hypercoagulability J:191844
hypotension J:125921
impaired leukocyte tethering or rolling J:191844
impaired righting response J:97108
increased circulating factor VIII level J:191844
increased circulating fibrinogen level J:191844
increased circulating osteocalcin level J:97108
increased eosinophil cell number J:191844
increased incidence of corneal inflammation J:110697
increased leukocyte cell number J:191844
increased lymphocyte cell number J:191844
increased megakaryocyte cell number J:191844
increased monocyte cell number J:110697
increased neutrophil cell number J:110697, J:191844
increased partial thromboplastin time J:191844
increased susceptibility to induced thrombosis J:191844
increased vasoconstriction J:191844
infertility J:110697
osteoporosis J:110697
postnatal growth retardation J:110697
premature aging J:110697, J:191844
premature death J:110697, J:116189
priapism J:191844
retarded hair growth J:110697
sacral vertebral fusion J:97108
normal skeleton phenotype J:97108
small seminal vesicle J:110697
thoracic vertebral fusion J:97108
thrombocytosis J:191844
vascular smooth muscle hyperplasia J:191844
weight loss J:97108, J:110697
Bmal1tm1Bra/Bmal1tm1Bra
involves: 129 		abnormal circadian behavior phase J:66502
abnormal circulating protein level J:155089
abnormal eye electrophysiology J:124157
abnormal glucose homeostasis J:131694
abnormal lipid homeostasis J:131694
abnormal locomotor activation J:66502
abnormal response to injury J:155089
arrhythmic circadian behavior persistence J:66502
decreased circulating progesterone level J:151819
decreased uterus weight J:115188
failure of embryo implantation J:151819
female infertility J:151819
normal homeostasis/metabolism phenotype J:151819
impaired gluconeogenesis J:131694
impaired wound healing J:193286
increased bone resorption J:115188
increased insulin sensitivity J:131694
increased osteoblast cell number J:115188
increased total fat pad weight J:115188
prolonged estrous cycle J:151819
normal skeleton phenotype J:115188
normal vision/eye phenotype J:124157
Bmal1tm1Bra/Bmal1tm1Bra
involves: 129/Sv * C57BL/6 		abnormal B cell differentiation J:118522
abnormal circadian sleep/wake cycle J:135933
abnormal sleep pattern J:135933
abnormal T cell subpopulation ratio J:118522
decreased B cell number J:118522, J:135933
decreased circulating glucose level J:135933
decreased follicular B cell number J:118522
decreased IgG1 level J:118522
decreased insulin secretion J:162641
decreased lymphocyte cell number J:118522, J:135933
decreased pancreatic islet number J:162641
decreased plasma anion gap J:135933
decreased transitional stage B cell number J:118522
fragmentation of sleep/wake states J:135933
increased blood urea nitrogen level J:135933
increased circulating alanine transaminase level J:135933
increased circulating aspartate transaminase level J:135933
increased neutrophil cell number J:135933
premature death J:135933
thrombocytosis J:135933
Bmal1tm1Bra/Bmal1tm1Bra
involves: 129/Sv * C57BL/6 * C57BL/6J 		abnormal hair cycle J:151782
abnormal hair cycle anagen phase J:151782
abnormal hair follicle matrix region morphology J:151782
Bmal1tm1Bra/Bmal1tm1Bra
Tg(ACTA1-Arntl)1Jt/0
involves: 129/Sv * C57BL/6J * CD-1 		abnormal circadian behavior J:116189
calcified calcaneal tendon J:116189
decreased body size J:116189
normal mortality/aging J:116189
Bmal1tm1Bra/Bmal1tm1Bra
Tg(Scg2-tTA)1Jt/0
Tg(tetO-Arntl)1Jt/0
involves: 129/Sv * C57BL/6J * CD-1 		abnormal locomotor activation J:116189
normal behavior/neurological phenotype J:116189
shortened circadian behavior period J:116189
Bmal1tm1Bra/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 		abnormal circadian behavior J:175596
shortened circadian behavior period J:175596
Bmal1tm1Bra/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10tm1.1(icre)Geno
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 		abnormal circadian behavior J:175596
Bmal1tm1Weit/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 		shortened circadian behavior period J:175596
Bmal1tm1Weit/Bmal1tm1Weit
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
involves: 129S4/SvJae * C57BL/6 		abnormal eye electrophysiology J:124157
Bmal1tm2Bra/Bmal1tm2Bra
Tg(Pdx1-cre)89.1Dam/0
involves: 129 * C57BL/6 * C57BL/6J * CBA * ICR 		abnormal pancreatic beta cell physiology J:162641
normal behavior/neurological phenotype J:162641
decreased insulin secretion J:162641
hyperglycemia J:162641
impaired glucose tolerance J:162641
Bmal1tm2Bra/Bmal1tm2Bra
Tg(Tek-cre)12Flv/0
involves: C3H * C57BL/6 * C57BL/6J 		abnormal protein level J:155089
abnormal response to injury J:155089
decreased locomotor activity J:155089
decreased mean systemic arterial blood pressure J:155089
increased heart rate J:155089
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory