Nrxn3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrxn3
neurexin III
MGI:1096389

7 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nrxn3^tm1Sud/Nrxn3^tm1Sud involves: 129 * C57BL/6	postnatal lethality, incomplete penetrance	J:89452
Nrxn3^tm2Sud/Nrxn3^tm2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:101977
Nrxn3^tm4.1Sud/Nrxn3^tm4.1Sud involves: 129S1/Sv * 129X1/SvJ	abnormal miniature excitatory postsynaptic currents	J:199997
	abnormal postsynaptic density morphology	J:199997
	abnormal synapse morphology	J:199997
	reduced long-term potentiation	J:199997
Nrxn3^tm4.1Sud/Nrxn3^tm4.1Sud involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:199997

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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