Nrxn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrxn1
neurexin I
MGI:1096391

29 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1⁺ C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H	increased circulating amylase level	J:211773
	increased lean body mass	J:211773
	increased neutrophil cell number	J:211773
	tremors	J:211773
Nrxn1^{tm1b(KOMP)Wtsi}/Nrxn1^{tm1b(KOMP)Wtsi} C57BL/6N-Nrxn1^{tm1b(KOMP)Wtsi}/H	abnormal bone structure	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased grip strength	J:211773
	decreased lymphocyte cell number	J:211773
	decreased pulmonary respiratory rate	J:211773
	decreased total body fat amount	J:211773
	impaired glucose tolerance	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
	tremors	J:211773
Nrxn1^tm1Sud/Nrxn1^tm1Sud involves: 129	abnormal nervous system physiology	J:115214
Nrxn1^tm1Sud/Nrxn1^tm1Sud involves: 129	decreased synaptic glutamate release	J:115214
Nrxn1^tm1Sud/Nrxn1^tm1Sud involves: 129 * C57BL/6	abnormal excitatory postsynaptic currents	J:153748
	abnormal miniature excitatory postsynaptic currents	J:153748
	abnormal motor learning	J:153748
	abnormal nest building behavior	J:153748
	normal behavior/neurological phenotype	J:153748
	decreased prepulse inhibition	J:153748
	increased grooming behavior	J:153748
Nrxn1^tm2Sud/Nrxn1^tm2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:101977
Nrxn1^tm3Sud/Nrxn1^tm3Sud B6.129-Nrxn1^tm3Sud	no abnormal phenotype detected	J:101977
Nrxn1^tm5Sud/Nrxn1^tm5Sud involves: C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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