Polr1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polr1a
polymerase (RNA) I polypeptide A
MGI:1096397

13 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polr1a^em1Knwea/Polr1a⁺ C57BL/6-Polr1a^em1Knwea	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
	normal reproductive system phenotype	J:335489
Polr1a^em1Knwea/Polr1a^em1Knwea C57BL/6-Polr1a^em1Knwea	embryonic lethality prior to organogenesis, complete penetrance	J:335489
Polr1a^em2Knwea/Polr1a⁺ C57BL/6-Polr1a^em2Knwea	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
	reproductive system phenotype	J:335489
Polr1a^em2Knwea/Polr1a^em2Knwea C57BL/6-Polr1a^em2Knwea	normal embryo phenotype	J:335489
Polr1a^em2Knwea/Polr1a^em2Knwea C57BL/6-Polr1a^em2Knwea	normal growth/size/body region phenotype	J:335489
Polr1a^em2Knwea/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
Polr1a^em2Knwea/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a⁺ C57BL/6-Polr1a^em3Knwea	embryo phenotype	J:335489
Polr1a^em3Knwea/Polr1a⁺ C57BL/6-Polr1a^em3Knwea	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^em3Knwea C57BL/6-Polr1a^em3Knwea	embryo phenotype	J:335489
Polr1a^em3Knwea/Polr1a^em3Knwea C57BL/6-Polr1a^em3Knwea	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^{tm1a(EUCOMM)Hmgu}/Polr1a⁺ involves: C57BL/6N	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
	normal reproductive system phenotype	J:335489
Polr1a^{tm1a(EUCOMM)Hmgu}/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality prior to organogenesis, complete penetrance	J:335489
Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a⁺ C57BL/6N-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay	abnormal retina outer nuclear layer morphology	J:211773
Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a^{tm1b(EUCOMM)Hmgu} C57BL/6N-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay	abnormal preimplantation embryo development	J:279207
	embryonic growth arrest	J:279207
	embryonic lethality before implantation, complete penetrance	J:279207
	failure of blastocyst formation	J:279207
	preweaning lethality, complete penetrance	J:211773
Polr1a^{tm1d(EUCOMM)Hmgu}/Polr1a⁺ involves: C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
	reproductive system phenotype	J:335489
Polr1a^{tm1d(EUCOMM)Hmgu}/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality prior to organogenesis, complete penetrance	J:335489

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24