Polr1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polr1a
polymerase (RNA) I polypeptide A
MGI:1096397

13 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polr1a^em1Knwea/Polr1a⁺ C57BL/6-Polr1a^em1Knwea	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
	normal reproductive system phenotype	J:335489
Polr1a^em1Knwea/Polr1a^em1Knwea C57BL/6-Polr1a^em1Knwea	embryonic lethality prior to organogenesis, complete penetrance	J:335489
Polr1a^em2Knwea/Polr1a⁺ C57BL/6-Polr1a^em2Knwea	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
	reproductive system phenotype	J:335489
Polr1a^em2Knwea/Polr1a^em2Knwea C57BL/6-Polr1a^em2Knwea	normal embryo phenotype	J:335489
Polr1a^em2Knwea/Polr1a^em2Knwea C57BL/6-Polr1a^em2Knwea	normal growth/size/body region phenotype	J:335489
Polr1a^em2Knwea/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
Polr1a^em2Knwea/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a⁺ C57BL/6-Polr1a^em3Knwea	embryo phenotype	J:335489
Polr1a^em3Knwea/Polr1a⁺ C57BL/6-Polr1a^em3Knwea	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^em3Knwea C57BL/6-Polr1a^em3Knwea	embryo phenotype	J:335489
Polr1a^em3Knwea/Polr1a^em3Knwea C57BL/6-Polr1a^em3Knwea	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^em3Knwea/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
Polr1a^{tm1a(EUCOMM)Hmgu}/Polr1a⁺ involves: C57BL/6N	normal embryo phenotype	J:335489
	normal growth/size/body region phenotype	J:335489
	normal reproductive system phenotype	J:335489
Polr1a^{tm1a(EUCOMM)Hmgu}/Polr1a^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality prior to organogenesis, complete penetrance	J:335489
Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a⁺ C57BL/6N-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay	abnormal retina outer nuclear layer morphology	J:211773
Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay	embryonic lethality before implantation, complete penetrance	J:279207
	failure of blastocyst formation	J:279207
	failure of zygotic cell division	J:279207
	increased cell death	J:279207
Polr1a^{tm1b(EUCOMM)Hmgu}/Polr1a^{tm1b(EUCOMM)Hmgu} C57BL/6N-Polr1a^{tm1b(EUCOMM)Hmgu}/Bay	preweaning lethality, complete penetrance	J:211773
Polr1a^{tm1d(EUCOMM)Hmgu}/Polr1a⁺ involves: C57BL/6N	embryo phenotype	J:335489
	growth/size/body region phenotype	J:335489
	reproductive system phenotype	J:335489
Polr1a^{tm1d(EUCOMM)Hmgu}/Polr1a^{tm1d(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality prior to organogenesis, complete penetrance	J:335489

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