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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Polr1a
polymerase (RNA) I polypeptide A
MGI:1096397
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N 		telencephalon hypoplasia J:335489
Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N 		telencephalon hypoplasia J:335489
Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N 		telencephalon hypoplasia J:335489
Foxg1tm1.1(cre)Ddmo/0
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1aem1Knwea/Polr1atm1c(EUCOMM)Hmgu
involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N 		telencephalon hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Mef2c-cre)2Blk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal heart right ventricle outflow tract morphology J:335489
absent heart right ventricle J:335489
enlarged heart J:335489
heart right ventricle hypoplasia J:335489
ventricular septal defect J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Sox10-cre)1Wdr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * CBA 		normal cardiovascular system phenotype J:335489
cleft chin J:335489
cleft palate J:335489
facial cleft J:335489
frontal bone hypoplasia J:335489
nasal bone hypoplasia J:335489
short mandible J:335489
temporal bone squamous part hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Wnt1-cre/Esr1*)10Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		decreased heart left ventricle wall thickness J:335489
embryonic lethality during organogenesis, complete penetrance J:335489
flat forehead J:335489
increased vascular permeability J:335489
lethality throughout fetal growth and development J:335489
persistent truncus arteriosus J:335489
pharyngeal arch artery hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Mef2c-cre)2Blk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal heart right ventricle outflow tract morphology J:335489
absent heart right ventricle J:335489
enlarged heart J:335489
heart right ventricle hypoplasia J:335489
ventricular septal defect J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Sox10-cre)1Wdr/0
Not Specified 		cardiovascular system phenotype J:335489
cleft chin J:335489
cleft palate J:335489
facial cleft J:335489
frontal bone hypoplasia J:335489
nasal bone hypoplasia J:335489
short mandible J:335489
temporal bone squamous part hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Wnt1-cre/Esr1*)10Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		decreased heart left ventricle wall thickness J:335489
embryonic lethality during organogenesis, complete penetrance J:335489
flat forehead J:335489
increased vascular permeability J:335489
lethality throughout fetal growth and development J:335489
persistent truncus arteriosus J:335489
pharyngeal arch artery hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1aem1Knwea/Polr1atm1c(EUCOMM)Hmgu
Tg(Sox10-cre)1Wdr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * CBA 		cleft palate J:335489
facial cleft J:335489
midline cleft upper lip J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1aem1Knwea/Polr1atm1c(EUCOMM)Hmgu
Tg(Wnt1-cre/Esr1*)10Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N 		normal cardiovascular system phenotype J:335489
facial cleft J:335489
flat forehead J:335489
lethality throughout fetal growth and development J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Mef2c-cre)2Blk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal heart right ventricle outflow tract morphology J:335489
absent heart right ventricle J:335489
enlarged heart J:335489
heart right ventricle hypoplasia J:335489
ventricular septal defect J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Sox10-cre)1Wdr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * CBA 		cardiovascular system phenotype J:335489
cleft chin J:335489
cleft palate J:335489
facial cleft J:335489
frontal bone hypoplasia J:335489
nasal bone hypoplasia J:335489
short mandible J:335489
temporal bone squamous part hypoplasia J:335489
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Wnt1-cre/Esr1*)10Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		decreased heart left ventricle wall thickness J:335489
embryonic lethality during organogenesis, complete penetrance J:335489
flat forehead J:335489
increased vascular permeability J:335489
lethality throughout fetal growth and development J:335489
persistent truncus arteriosus J:335489
pharyngeal arch artery hypoplasia J:335489
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory