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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptgis
prostaglandin I2 (prostacyclin) synthase
MGI:1097156
34 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptgisem1(IMPC)Mbp/Ptgisem1(IMPC)Mbp
C57BL/6N-Ptgisem1(IMPC)Mbp/MbpMmucd 		abnormal brain morphology J:211773
abnormal kidney morphology J:211773
abnormal lymph node morphology J:211773
abnormal testis morphology J:211773
abnormal thymus morphology J:211773
decreased kidney weight J:211773
decreased mean corpuscular volume J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
increased brain size J:211773
increased heart weight J:211773
increased mean corpuscular hemoglobin concentration J:211773
increased red blood cell distribution width J:211773
polycystic kidney J:211773
small kidney J:211773
small testis J:211773
Ptgistm1Tada/Ptgistm1Tada
B6.129-Ptgistm1Tada 		abnormal aorta tunica adventitia morphology J:103380
abnormal aorta tunica media morphology J:103380
abnormal aorta wall morphology J:103380
abnormal kidney morphology J:103380
abnormal renal tubule morphology J:103380
abnormal thoracic aorta morphology J:103380
abnormal thromboxane level J:103380
decreased prostaglandin level J:103380
dilated renal glomerular capsule J:103380
increased blood urea nitrogen level J:103380
increased circulating creatinine level J:103380
increased prostaglandin level J:103380
increased systemic arterial blood pressure J:103380
kidney atrophy J:103380
kidney cortex atrophy J:103380
kidney cyst J:103380
kidney vascular congestion J:103380
renal fibrosis J:103380
renal necrosis J:103380
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory