Ogg1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ogg1
8-oxoguanine DNA-glycosylase 1
MGI:1097693

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ogg1^tm1Tld/Ogg1^tm1Tld involves: 129P2/OlaHsd	no abnormal phenotype detected	J:58517
Ogg1^tm1Tno/Ogg1^tm1Tno involves: 129S4/SvJae * C57BL/6J	abnormal DNA repair	J:61684, J:84649
Ogg1^tm1Tno/Ogg1^tm1Tno involves: 129S4/SvJae * C57BL/6J	normal liver/biliary system phenotype	J:84649
Ogg1^tm1Tno/Ogg1^tm1Tno Tg(gptdelta)1Nmi/0 involves: 129S4/SvJae * C57BL/6J	abnormal cell physiology	J:61684, J:84649
Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6J	increased lung adenoma incidence	J:82287
Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6J	increased lung carcinoma incidence	J:82287
Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6JJcl	decreased locomotor activity	J:193978
	decreased vertical activity	J:193978
	increased susceptibility to neuronal excitotoxicity	J:193978
	microgliosis	J:193978
	neurodegeneration	J:193978

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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