Degs1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Degs1
delta 4-desaturase, sphingolipid 1
MGI:1097711

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Degs1^em1(IMPC)Mbp/Degs1⁺ C57BL/6NCrl-Degs1^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
Degs1^em1(IMPC)Mbp/Degs1^em1(IMPC)Mbp C57BL/6NCrl-Degs1^em1(IMPC)Mbp/MbpMmucd	preweaning lethality, complete penetrance	J:211773
Degs1^{Gt(OST368559)Lex}/Degs1⁺ involves: 129S5/SvEvBrd	abnormal ceramide level	J:203554
	increased insulin sensitivity	J:203554
	increased muscle cell glucose uptake	J:203554
Degs1^{Gt(OST368559)Lex}/Degs1^{Gt(OST368559)Lex} involves: 129S5/SvEvBrd	abnormal ceramide level	J:203554
	abnormal hematopoietic system morphology/development	J:203554
	abnormal homeostasis	J:203554
	decreased body length	J:203554
	decreased body size	J:203554
	decreased body weight	J:203554
	decreased bone mineral content	J:203554
	decreased bone mineral density	J:203554
	decreased lean body mass	J:203554
	decreased liver function	J:203554
	increased circulating alanine transaminase level	J:203554
	increased circulating alkaline phosphatase level	J:203554
	increased circulating bilirubin level	J:203554
	postnatal growth retardation	J:203554
	premature death	J:203554
	preweaning lethality, incomplete penetrance	J:203554
	scaly skin	J:203554
	sparse hair	J:203554
	tremors	J:203554

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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