Kif14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif14
kinesin family member 14
MGI:1098226

34 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif14^lag/Kif14^lag B6.D2(129X1)-Kif14^lag	abnormal cerebellar cortex morphology	J:195809
	abnormal cerebellar granule cell migration	J:195809
	abnormal cerebral cortex morphology	J:195809
	abnormal gait	J:195809
	abnormal locomotor coordination	J:195809
	abnormal motor capabilities/coordination/movement	J:195809
	abnormal olfactory bulb morphology	J:195809
	abnormal oligodendrocyte physiology	J:195809
	abnormal Purkinje cell dendrite morphology	J:195809
	abnormal spinal cord morphology	J:195809
	ataxia	J:195809
	cerebellum hypoplasia	J:195809
	decreased body size	J:195809
	decreased body weight	J:195809
	decreased brain weight	J:195809
	decreased cell proliferation	J:195809
	demyelination	J:195809
	ectopic cerebral cortex pyramidal cells	J:195809
	ectopic Purkinje cell	J:195809
	impaired balance	J:195809
	increased apoptosis	J:195809
	microcephaly	J:195809
	postnatal lethality, complete penetrance	J:195809
	slow postnatal weight gain	J:195809
	small olfactory bulb	J:195809
	thin cerebral cortex	J:195809
	tremors	J:195809
	weakness	J:195809
Kif14^lag/Kif14^lag Tg(CAG-Kif14)28LTskk/0 involves: 129X1/SvJ * C57BL/6JJmsSlc * C57BL/6NJcl * DBA/2NJcl	normal behavior/neurological phenotype	J:195809
	normal nervous system phenotype	J:195809
Kif14^tm1Tskk/Kif14^tm1Tskk C57BL/6N-Kif14^tm1Tskk	abnormal cerebellar cortex morphology	J:195809
	abnormal cerebral cortex morphology	J:195809
	abnormal gait	J:195809
	abnormal hippocampus morphology	J:195809
	abnormal spinal cord morphology	J:195809
	ataxia	J:195809
	decreased brain size	J:195809
	demyelination	J:195809
	flat head	J:195809
	impaired balance	J:195809
	optic nerve hypoplasia	J:195809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24