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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stag2
STAG2 cohesin complex component
MGI:1098583
36 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Stag2tm1.1Alos/Y
involves: 129S6/SvEvTac * C57BL/6NCrl 		abnormal enterocyte proliferation J:298088
abnormal hematopoietic stem cell physiology J:298088
abnormal intestine morphology J:298088
abnormal mitosis J:298088
cellular necrosis J:298088
decreased body weight J:298088
decreased fibroblast proliferation J:298088
normal hematopoietic system phenotype J:298088
increased fibroblast apoptosis J:298088
normal neoplasm J:298088
premature death J:298088
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Stag2tm1.1Alos/Stag2tm1.1Alos
involves: 129S6/SvEvTac * C57BL/6NCrl 		abnormal enterocyte proliferation J:298088
abnormal hematopoietic stem cell physiology J:298088
abnormal intestine morphology J:298088
abnormal mitosis J:298088
cellular necrosis J:298088
decreased body weight J:298088
decreased fibroblast proliferation J:298088
hematopoietic system phenotype J:298088
increased fibroblast apoptosis J:298088
neoplasm J:298088
premature death J:298088
Stag2tm1.1Alos/Y
Tg(CAG-cre)1Nagy/0
involves: 129S6/SvEvTac * C57BL/6NCrl 		abnormal cardiac outflow tract development J:298088
abnormal heart development J:298088
common atrium J:298088
decreased cell proliferation J:298088
decreased embryo size J:298088
decreased heart right ventricle size J:298088
embryonic growth retardation J:298088
embryonic lethality during organogenesis, complete penetrance J:298088
Stag2tm1.1Soga/Y
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6J * C57BL/6N * CBA/J 		abnormal hematopoietic precursor cell morphology J:289000
abnormal hematopoietic stem cell physiology J:289000
abnormal hematopoietic system morphology/development J:289000
decreased B cell number J:289000
decreased common lymphocyte progenitor cell number J:289000
decreased erythroid progenitor cell number J:289000
decreased leukocyte cell number J:289000
decreased megakaryocyte-erythroid progenitor cell number J:289000
enlarged spleen J:289000
extramedullary hematopoiesis J:289000
increased common myeloid progenitor cell number J:289000
increased granulocyte monocyte progenitor cell number J:289000
increased granulocyte number J:289000
increased hematopoietic stem cell number J:289000
increased monocyte cell number J:289000
increased red blood cell distribution width J:289000
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory