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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tmem38b
transmembrane protein 38B
MGI:1098718
28 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tmem38bem1(IMPC)Mbp/Tmem38b+
C57BL/6NCrl-Tmem38bem1(IMPC)Mbp/MbpMmucd 		abnormal placenta morphology J:211773
embryonic growth retardation J:211773
Tmem38bem1(IMPC)Mbp/Tmem38bem1(IMPC)Mbp
C57BL/6NCrl-Tmem38bem1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
embryonic growth retardation J:211773
microphthalmia J:211773
preweaning lethality, complete penetrance J:211773
Tmem38btm1Hta/Tmem38btm1Hta
involves: 129S4/SvJae 		neonatal lethality J:122817
Tmem38btm1Hta/Tmem38btm1Hta
involves: 129S4/SvJae * C57BL/6J 		abnormal alveolar lamellar body morphology J:150355
abnormal calcium ion homeostasis J:150355
abnormal lung development J:150355
abnormal lung saccule morphology J:150355
abnormal pulmonary alveolus epithelial cell morphology J:150355
abnormal respiratory system physiology J:150355
abnormal surfactant composition J:150355
abnormal surfactant secretion J:150355
abnormal type II pneumocyte morphology J:150355
acidosis J:150355
atelectasis J:150355
cyanosis J:150355
decreased alveolar lamellar body number J:150355
hypoxia J:150355
impaired lung alveolus development J:150355
neonatal lethality, complete penetrance J:150355
pulmonary vascular congestion J:150355
respiratory distress J:150355
respiratory failure J:150355
small alveolar lamellar bodies J:150355
thick pulmonary interalveolar septum J:150355
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory