Erc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Erc2
ELKS/RAB6-interacting/CAST family member 2
MGI:1098749

16 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Erc2^tm1.1Sud/Erc2^tm1.1Sud involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal CNS synaptic transmission	J:155764
	abnormal inhibitory postsynaptic currents	J:155764
	abnormal synapse morphology	J:155764
	abnormal synaptic neurotransmitter level	J:155764
	abnormal synaptic vesicle number	J:155764
	increased exploration in new environment	J:155764
Erc2^tm1.1Sud/Erc2^tm1.1Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal CNS synaptic transmission	J:133656
	abnormal inhibitory postsynaptic currents	J:133656
	abnormal synaptic neurotransmitter level	J:133656
Erc2^tm1.2Sud/Erc2^tm1.2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal inhibitory postsynaptic currents	J:155764
Erc2^tm1Toh/Erc2^tm1Toh Not Specified	abnormal eye electrophysiology	J:187689
	abnormal retina bipolar cell morphology	J:187689
	abnormal retina horizontal cell morphology	J:187689
	abnormal retina morphology	J:187689
	abnormal retina outer nuclear layer morphology	J:187689
	abnormal retina outer plexiform layer morphology	J:187689
	abnormal retina rod cell morphology	J:187689
	abnormal rod electrophysiology	J:187689
	abnormal vision	J:187689
	thin retina outer plexiform layer	J:187689

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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