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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pik3r2
phosphoinositide-3-kinase regulatory subunit 2
MGI:1098772
13 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pik3r2em1Gldn/Pik3r2em1Gldn
C57BL/6-Pik3r2em1Gldn 		abnormal cell nucleus morphology J:304006
dilated brain ventricle J:304006
increased brain size J:304006
increased brain weight J:304006
normal nervous system phenotype J:304006
neuron hypertrophy J:304006
normal reproductive system phenotype J:304006
thickened cerebral cortex J:304006
Pik3r2tm1e(KOMP)Wtsi/Pik3r2tm1e(KOMP)Wtsi
C57BL/6N-Pik3r2tm1e(KOMP)Wtsi/Wtsi 		decreased body weight J:175295
decreased circulating creatinine level J:175295
Pik3r2tm1Lca/Pik3r2tm1Lca
involves: 129S6/SvEvTac 		decreased circulating glucose level J:73703
decreased circulating insulin level J:73703
increased insulin sensitivity J:73703
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory