Pik3r2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pik3r2
phosphoinositide-3-kinase regulatory subunit 2
MGI:1098772

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pik3r2^em1Gldn/Pik3r2^em1Gldn C57BL/6-Pik3r2^em1Gldn	abnormal cell nucleus morphology	J:304006
	dilated brain ventricle	J:304006
	increased brain size	J:304006
	increased brain weight	J:304006
	normal nervous system phenotype	J:304006
	neuron hypertrophy	J:304006
	normal reproductive system phenotype	J:304006
	thickened cerebral cortex	J:304006
Pik3r2^{tm1e(KOMP)Wtsi}/Pik3r2^{tm1e(KOMP)Wtsi} C57BL/6N-Pik3r2^{tm1e(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating creatinine level	J:175295
Pik3r2^tm1Lca/Pik3r2^tm1Lca involves: 129S6/SvEvTac	decreased circulating glucose level	J:73703
	decreased circulating insulin level	J:73703
	increased insulin sensitivity	J:73703

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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