Rhpn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rhpn1
rhophilin, Rho GTPase binding protein 1
MGI:1098783

24 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rhpn1^{tm1b(KOMP)Wtsi}/Rhpn1^{tm1b(KOMP)Wtsi} C57BL/6N-Rhpn1^{tm1b(KOMP)Wtsi}/Ucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hemoglobin content	J:211773
	enlarged heart	J:211773
	hyperactivity	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased heart weight	J:211773
	increased mean platelet volume	J:211773
Rhpn1^tm1Ktry/Rhpn1^tm1Ktry B6.129X1-Rhpn1^tm1Ktry	albuminuria	J:276466
Rhpn1^tm1Ktry/Rhpn1^tm1Ktry involves: 129X1/SvJ * C57BL/6	abnormal glomerular mesangium morphology	J:276466
	abnormal podocyte foot process morphology	J:276466
	abnormal podocyte morphology	J:276466
	abnormal podocyte slit diaphragm morphology	J:276466
	abnormal renal glomerulus morphology	J:276466
	albuminuria	J:276466
	enlarged kidney	J:276466
	glomerulosclerosis	J:276466
	increased renal glomerulus basement membrane thickness	J:276466
	podocyte foot process effacement	J:276466
	podocyte microvillus transformation	J:276466
	renal cast	J:276466
	renal glomerular synechia	J:276466

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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