Sepsecs Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
MGI:1098791

20 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sepsecs^em1(IMPC)Tcp/Sepsecs⁺ C57BL/6NCrl-Sepsecs^em1(IMPC)Tcp/Cmmr	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	increased circulating calcium level	J:211773
	thick skin	J:211773
Sepsecs^em1(IMPC)Tcp/Sepsecs^em1(IMPC)Tcp C57BL/6NCrl-Sepsecs^em1(IMPC)Tcp/Cmmr	abnormal egg cylinder morphology	J:279207
	disorganized extraembryonic tissue	J:279207
	embryonic growth retardation	J:279207
	embryonic lethality between implantation and placentation, complete penetrance	J:279207
	embryonic lethality prior to organogenesis	J:211773
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
	preweaning lethality, complete penetrance	J:211773
Sepsecs^tm1.1Usch/Sepsecs^tm1.1Usch 129.Cg-Sepsecs^tm1.1Usch	abnormal respiration	J:315052
	perinatal lethality, complete penetrance	J:315052
Sepsecs^tm1.1Usch/Sepsecs^tm1.1Usch B6.Cg-Sepsecs^tm1.1Usch	absent gastric milk in neonates	J:315052
	cyanosis	J:315052
	decreased birth weight	J:315052
	decreased pulmonary respiratory rate	J:315052
	perinatal lethality, complete penetrance	J:315052
Sepsecs^tm1Usch/Sepsecs^tm1Usch involves: 129S6/SvEvTac * C57BL/6J	embryonic growth arrest	J:315052
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:315052

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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