Cdk12 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdk12
cyclin dependent kinase 12
MGI:1098802

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdk12^em1(IMPC)Tcp/Cdk12⁺ C57BL/6NCrl-Cdk12^em1(IMPC)Tcp/Tcp	abnormal liver morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased exploration in new environment	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	enlarged spleen	J:211773
	enlarged urinary bladder	J:211773
	increased heart weight	J:211773
	increased red blood cell distribution width	J:211773
	increased spleen weight	J:211773
Cdk12^em1(IMPC)Tcp/Cdk12^em1(IMPC)Tcp C57BL/6NCrl-Cdk12^em1(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Cdk12^tm1.2Mjfn/Cdk12^tm1.2Mjfn involves: FVB/N	abnormal inner cell mass morphology	J:242195
	abnormal trophoblast giant cell morphology	J:242195
	chromosomal instability	J:242195
	embryonic lethality between implantation and somite formation, complete penetrance	J:242195
	increased apoptosis	J:242195

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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