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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pex5
peroxisomal biogenesis factor 5
MGI:1098808
50 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pex5tm1Baes/Pex5tm1Baes
involves: 129S1/Sv * 129X1/SvJ 		abnormal cerebral cortex morphology J:42719
abnormal kidney morphology J:42719
abnormal liver morphology J:42719
decreased body weight J:42719
delayed brain development J:42719
delayed intestine development J:42719
delayed kidney development J:42719
embryonic growth retardation J:42719
muscle weakness J:42719
postnatal lethality, complete penetrance J:42719
respiratory distress J:42719
Pex5tm1Pec/Pex5tm1Pec
Cnptm1(cre)Kan/Cnp+
involves: 129S1/Sv * 129X1/SvJ 		abnormal axon morphology J:123503
abnormal brain white matter morphology J:123503
abnormal breathing pattern J:123503
abnormal glial cell morphology J:123503
abnormal inflammatory response J:123503
abnormal myelination J:123503
abnormal oligodendrocyte morphology J:123503
ataxia J:123503
gliosis J:123503
hindlimb paralysis J:123503
hindlimb paresis J:123503
kyphosis J:123503
microgliosis J:123503
premature death J:123503
tremors J:123503
Pex5tm1Pec/Pex5tm1Pec
Plekha5Tg(AMH-cre)1Flor/Plekha5+
involves: 129S1/Sv * 129X1/SvJ 		abnormal seminiferous tubule morphology J:108368
abnormal testis morphology J:108368
decreased testis weight J:108368
male infertility J:108368
seminiferous tubule degeneration J:108368
Pex5tm1Pec/Pex5tm1Pec
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA 		abnormal bile salt homeostasis J:121804
abnormal blood homeostasis J:112503
abnormal cell morphology J:112503
abnormal endoplasmic reticulum morphology J:112503
abnormal fatty acid beta-oxidation J:121804
abnormal glucose homeostasis J:112503
abnormal liver morphology J:112503
abnormal lysosome morphology J:112503
abnormal mitochondrial ATP synthesis coupled electron transport J:112503
abnormal mitochondrial crista morphology J:112503
abnormal mitochondrial inner membrane morphology J:112503
abnormal mitochondrial shape J:112503
abnormal postnatal growth J:112503
abnormal respiratory electron transport chain J:112503
decreased body weight J:112503
enlarged liver J:112503
increased circulating lactate level J:112503
increased liver tumor incidence J:112503
liver hyperplasia J:112503
normal liver/biliary system phenotype J:112503
slow postnatal weight gain J:112503
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory