Ucp3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ucp3
uncoupling protein 3 (mitochondrial, proton carrier)
MGI:1099787

12 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ucp3^tm1Brnd/Ucp3^tm1Brnd B6.Cg-Ucp3^tm1Brnd	abnormal mitochondrial physiology	J:73905
Ucp3^tm1Brnd/Ucp3^tm1Brnd Not Specified	decreased skeletal muscle triglyceride level	J:106901
Ucp3^tm1Lowl/Ucp3^tm1Lowl involves: 129S4/SvJae * C57BL/6	abnormal cellular respiration	J:62313
	abnormal mitochondrial ATP synthesis coupled electron transport	J:102104
	normal growth/size/body region phenotype	J:62313
	normal homeostasis/metabolism phenotype	J:62313
	increased fatty acids level	J:62313
Ucp3^tm1Rei/Ucp3^tm1Rei involves: 129S6/SvEvTac	abnormal epididymal fat pad morphology	J:142293
	improved glucose tolerance	J:142293
	increased insulin sensitivity	J:142293
Ucp3^tm1Rei/Ucp3^tm1Rei involves: 129S6/SvEvTac * Black Swiss	abnormal mitochondrial physiology	J:62312
	decreased circulating free fatty acids level	J:62312
	decreased circulating glucose level	J:62312

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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