Hip1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hip1
huntingtin interacting protein 1
MGI:1099804

45 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gdpd3^em1Tsr/Gdpd3^em1Tsr Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr} involves: C57BL/6 * C57BL/6J	lordokyphosis	J:267987
Hip1^tm3Tsr/Hip1^tm3Tsr Hip1r^tm1Tsr/Hip1r^tm1Tsr involves: 129X1/SvJ	lordokyphosis	J:267987
Hip1^tm3Tsr/Hip1^tm3Tsr Hip1r^tm1Tsr/Hip1r^tm1Tsr involves: 129X1/SvJ * C57BL/6	abnormal spine curvature	J:89961
	abnormal vertebral body morphology	J:89961
	abnormal vertebral column morphology	J:89961
	decreased body size	J:89961
	decreased body weight	J:89961
	hunched posture	J:89961
	lordokyphosis	J:89961
	premature death	J:89961
Hip1^tm3Tsr/Hip1^{tm5.2(HIP1)Tsr} Hip1r^tm1Tsr/Hip1r^tm1Tsr involves: 129X1/SvJ * C57BL/6 * SJL	normal skeleton phenotype	J:267987
Hip1^tm4Tsr/Hip1⁺ Runx1^tm3Dow/Runx1⁺ Tg(Mx1-cre)1Cgn/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal bone marrow cell morphology/development	J:151974
	abnormal bone marrow cell physiology	J:151974
	abnormal definitive hematopoiesis	J:151974
	abnormal liver morphology	J:151974
	abnormal liver parenchyma morphology	J:151974
	abnormal lung morphology	J:151974
	abnormal myelopoiesis	J:151974
	abnormal spleen B cell follicle morphology	J:151974
	abnormal spleen morphology	J:151974
	abnormal tumor morphology	J:151974
	decreased bone marrow cell number	J:151974
	decreased common myeloid progenitor cell number	J:151974
	decreased hematopoietic stem cell number	J:151974
	enlarged liver	J:151974
	enlarged spleen	J:151974
	extramedullary hematopoiesis	J:151974
	increased chronic myelocytic leukemia incidence	J:151974
	increased granulocyte number	J:151974
	increased hematopoietic stem cell number	J:151974
	increased leukocyte cell number	J:151974
	increased liver weight	J:151974
	increased neutrophil cell number	J:151974
	increased spleen red pulp amount	J:151974
	increased spleen weight	J:151974
	postnatal lethality	J:151974
	spleen hyperplasia	J:151974
Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr} involves: C57BL/6	abnormal amino acid level	J:267987
	abnormal enzyme/coenzyme level	J:267987
	abnormal metabolism	J:267987
	abnormal vertebral column morphology	J:267987
	abnormal vitamin homeostasis	J:267987
	decreased acetylcholine level	J:267987
	decreased body weight	J:267987
	decreased cystathionine level	J:267987
	decreased phosphocholine level	J:267987
	lordokyphosis	J:267987
	weight loss	J:267987
Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr} Tg(GFAP-cre)25Mes/0 involves: C57BL/6 * FVB/N	lordokyphosis	J:267987
Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr} Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * C57BL/6J * CBA/J	normal growth/size/body region phenotype	J:267987
	normal skeleton phenotype	J:267987
Hip1^{tm5.2(HIP1)Tsr}/Hip1^{tm5.2(HIP1)Tsr} involves: C57BL/6 * SJL	normal growth/size/body region phenotype	J:267987
	normal homeostasis/metabolism phenotype	J:267987
	normal skeleton phenotype	J:267987

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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