About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pkd2
polycystin 2, transient receptor potential cation channel
MGI:1099818
11 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Hdac5tm1Eno/Hdac5+
Pkd2tm2Som/Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		kidney cyst J:158762
Hdac5tm1Eno/Hdac5tm1Eno
Pkd2tm2Som/Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		lethality throughout fetal growth and development, complete penetrance J:158762
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd2tm3Som/Pkd2tm3Som
Tg(Pkhd1-cre)1Igr/0
involves: 129S4/SvJae * C57BL/6 		decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
kidney cyst J:244067
premature death J:244067
Pde1aem1Cjwa/Pde1aem1Cjwa
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * C57BL/6N * SJL 		kidney cyst J:246596
Pkd1tm1.1Pcha/Pkd1+
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
premature death J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm2Som/Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1Som/Pkd1+
Pkd2tm2Som/Pkd2+
involves: 129/Sv * C57BL/6 * SJL 		kidney cyst J:78422
liver cyst J:78422
Pkd1l1rks/Pkd1l1+
Pkd2lrm4/Pkd2+
C3.Cg-Pkd2lrm4 Pkd1l1rks 		no abnormal phenotype detected J:170490
Pkd2tm2Som/Pkd2+
Pkhd1tm1Gwu/Pkhd1tm1Gwu
involves: 129/Sv * C57BL/6J * SJL 		dilated renal tubule J:143394
kidney cyst J:143394
Pkd2tm2Som/Pkd2+
Prkcshtm1Som/Prkcshtm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
increased kidney weight J:188763
kidney cyst J:188763
Pkd2tm2Som/Pkd2+
Sec63tm1Som/Sec63tm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
kidney cyst J:188763
Pkd2tm3Som/Pkd2tm3Som
Tg(Pkd1)248Som/0
Tg(Pkhd1-cre)1Igr/0
involves: C57BL/6J * SJL/J 		kidney cyst J:188763
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory