Nrp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrp2
neuropilin 2
MGI:1100492

43 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nrp2^{Gt(GST039)Byg}/Nrp2^{Gt(GST039)Byg} either: B6.129P2-Nrp2^{Gt(GST039)Byg} or (involves: 129P2/OlaHsd * CD-1)	abnormal anterior commissure morphology	J:60158
	abnormal anterior commissure pars posterior morphology	J:60158
	abnormal habenula morphology	J:60158
	abnormal hippocampal mossy fiber morphology	J:60158
	abnormal oculomotor nerve morphology	J:60158
	abnormal spinal cord dorsal column morphology	J:60158
	abnormal trigeminal nerve morphology	J:60158
	absent trochlear nerve	J:60158
	normal nervous system phenotype	J:60158
Nrp2^{Gt(pMS-1)1Hmy}/Nrp2^{Gt(pMS-1)1Hmy} B6.129S1-Nrp2^{Gt(pMS-1)1Hmy}	abnormal innervation	J:121340
	decreased body size	J:121340
	normal nervous system phenotype	J:121340
	perinatal lethality, incomplete penetrance	J:121340
Nrp2^tm1.2Mom/Nrp2⁺ involves: 129P2/OlaHsd * C57BL/6 * FVB/NJ	abnormal dendrite morphology	J:166116
	abnormal dendritic spine morphology	J:166116
	abnormal nervous system physiology	J:166116
	abnormal synaptic plasticity	J:166116
	environmentally induced seizures	J:166116
	increased susceptibility to pharmacologically induced seizures	J:166116
	myoclonus	J:166116
	seizures	J:166116
Nrp2^tm1.2Mom/Nrp2^tm1.2Mom involves: 129P2/OlaHsd	abnormal lymphatic system physiology	J:226501
	abnormal lymphatic vessel endothelial cell morphology	J:226501
	abnormal lymphatic vessel morphology	J:226501
	lymphatic vessel hyperplasia	J:226501
Nrp2^tm1.2Mom/Nrp2^tm1.2Mom involves: 129P2/OlaHsd * C57BL/6 * FVB/NJ	abnormal hippocampus neuron morphology	J:166116
	environmentally induced seizures	J:166116
	increased susceptibility to induced morbidity/mortality	J:166116
	increased susceptibility to pharmacologically induced seizures	J:166116
	myoclonus	J:166116
	postnatal lethality, incomplete penetrance	J:166116
	seizures	J:166116
Nrp2^tm1.2Mom/Nrp2^tm1.2Mom involves: 129P2/OlaHsd * C57BL/6 * SJL/J	abnormal axon guidance	J:76686
	abnormal olfactory neuron innervation pattern	J:76686
	abnormal sensory neuron innervation pattern	J:76686
	abnormal vomeronasal sensory neuron morphology	J:76686
	abnormal vomeronasal sensory neuron physiology	J:76686
	hydrocephaly	J:76686
	postnatal growth retardation	J:76686
	prenatal lethality, incomplete penetrance	J:76686
	reduced fertility	J:76686
Nrp2^tm1Ddg/Nrp2^tm1Ddg involves: C57BL/6	abnormal lymphangiogenesis	J:156869
Nrp2^tm1Ddg/Nrp2^tm1Ddg involves: C57BL/6	decreased cell proliferation	J:156869
Nrp2^tm1Ddg/Nrp2^tm1Ddg Not Specified	normal vision/eye phenotype	J:172268
Nrp2^tm1Mkl/Nrp2^tm1Mkl C.Cg-Nrp2^tm1Mkl	normal embryo phenotype	J:75477
Nrp2^tm1Mkl/Nrp2^tm1Mkl C.Cg-Nrp2^tm1Mkl	normal mortality/aging	J:75477
Nrp2^tm1Mkl/Nrp2^tm1Mkl involves: ICR	abnormal nervous system development	J:134616
Nrp2^tm1Mkl/Nrp2^tm1Mkl involves: ICR	abnormal neuronal migration	J:134616

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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