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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ercc6
excision repair cross-complementing rodent repair deficiency, complementation group 6
MGI:1100494
23 phenotypes from 1 allele in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ercc6tm1Gvh/Ercc6tm1Gvh
B6J.129P2-Ercc6tm1Gvh 		cochlear inner hair cell degeneration J:219993
cochlear outer hair cell degeneration J:219993
decreased distortion product otoacoustic emission amplitude J:219993
degeneration of organ of Corti supporting cells J:219993
Deiters cell degeneration J:219993
impaired hearing J:219993
increased or absent threshold for auditory brainstem response J:219993
pillar cell degeneration J:219993
Ercc6tm1Gvh/Ercc6tm1Gvh
involves: 129P2/OlaHsd * C57BL/6J 		astrocytosis J:179808
increased cellular sensitivity to ultraviolet irradiation J:122013
microgliosis J:179808
postnatal growth retardation J:122013
retina degeneration J:122013
Ercc6tm1Gvh/Ercc6tm1Gvh
involves: 129P2/OlaHsd * CBA/CaJ 		impaired hearing J:219993
increased or absent threshold for auditory brainstem response J:219993
Ercc6tm1Gvh/Ercc6tm1Gvh
involves: 129P2/OlaHsd * FVB 		abnormal cell physiology J:40211
abnormal locomotor behavior J:40211
circling J:40211
decreased body weight J:40211
impaired balance J:40211
impaired coordination J:40211
increased cellular sensitivity to ultraviolet irradiation J:40211
increased incidence of induced tumors J:40211
photophobia J:40211
photosensitivity J:40211
skin photosensitivity J:40211
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory