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Symbol Name ID |
Mre11a
MRE11A homolog A, double strand break repair nuclease MGI:1100512 |
Excel File
| Allelic Composition Genetic Background |
Annotated Term | Reference |
| Lig4tm1Icrf/Lig4tm1Icrf Mre11atm1Jpt/Mre11atm1Jpt involves: 129 * 129S7/SvEvBrd |
decreased cellular sensitivity to ionizing radiation | J:144172 |
| neonatal lethality, complete penetrance | J:144172 | |
| Lig4tm1Pmc/Lig4tm1Pmc Mre11atm1Jpt/Mre11atm1Jpt Tg(Nes-cre)1Kln/0 involves: 129S1/SvImJ * 129S7/SvEvBrd * C57BL/6 * SJL |
ataxia | J:144172 |
| normal nervous system phenotype | J:144172 | |
| Mre11atm1Jpt/Mre11a+ Rad50tm2Jpt/Rad50tm2Jpt involves: 129S7/SvEvBrd * C57BL/6 |
abnormal hematopoietic system morphology/development | J:103922 |
| anemia | J:103922 | |
| increased lymphoma incidence | J:103922 | |
| premature death | J:103922 | |
| Mre11atm1Jpt/Mre11atm1Jpt Rad50tm2Jpt/Rad50tm2Jpt involves: 129S7/SvEvBrd * C57BL/6 |
abnormal cell cycle checkpoint function | J:103922 |
| chromosome breakage | J:103922 | |
| normal hematopoietic system phenotype | J:103922 | |
| increased cellular sensitivity to ionizing radiation | J:103922 | |
| increased lymphoma incidence | J:103922 | |
| premature death | J:103922 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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