About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nr2e1
nuclear receptor subfamily 2, group E, member 1
MGI:1100526
69 phenotypes from 5 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Nr2e1frc/Nr2e1frc
either: B6.129-Nr2e1frc or 129P3/JEms.Cg-Nr2e1frc or B6129F1-Nr2e1frc 		abnormal aggression-related behavior J:71869
abnormal brain commissure morphology J:71869
abnormal cerebral hemisphere morphology J:71869
abnormal eye electrophysiology J:71869
abnormal nursing J:71869
abnormal optic nerve morphology J:71869
abnormal retina ganglion layer morphology J:71869
abnormal retina inner plexiform layer morphology J:71869
abnormal retina morphology J:71869
abnormal retina nerve fiber layer morphology J:71869
abnormal retina photoreceptor layer morphology J:71869
abnormal retina vasculature morphology J:71869
abnormal sensory capabilities/reflexes/nociception J:71869
decreased body length J:71869
decreased body size J:71869
decreased body weight J:71869
decreased brain size J:71869
decreased exploration in new environment J:71869
decreased total body fat amount J:71869
enlarged brain ventricles J:71869
forebrain hypoplasia J:71869
hydrocephaly J:71869
increased aggression towards humans J:71869
increased aggression towards mice J:71869
persistence of hyaloid vascular system J:71869
reduced female fertility J:71869
slow postnatal weight gain J:71869
thin retina inner nuclear layer J:71869
Nr2e1frc/Nr2e1frc
involves: 129P2/OlaHsd * 129S1/SvImJ 		abnormal cerebral hemisphere morphology J:183689
abnormal eye electrophysiology J:183689
abnormal neuronal precursor proliferation J:183689
abnormal retina ganglion cell morphology J:183689
abnormal retina vasculature morphology J:183689
small olfactory bulb J:183689
thin retina inner nuclear layer J:183689
thin retina outer nuclear layer J:183689
Nr2e1tm1Gsc/Nr2e1tm1Gsc
involves: 129 * C57BL/6 		abnormal amygdala morphology J:44679
abnormal cortical intermediate zone morphology J:44679
abnormal dentate gyrus morphology J:44679
abnormal entorhinal cortex morphology J:44679
abnormal hippocampal mossy fiber morphology J:44679
abnormal learning/memory/conditioning J:44679
abnormal limbic system morphology J:44679
abnormal maternal nurturing J:44679
abnormal olfactory cortex morphology J:44679
decreased anterior commissure size J:44679
decreased brain size J:44679
decreased subiculum size J:44679
increased aggression J:44679
slow postnatal weight gain J:44679
small olfactory bulb J:44679
Nr2e1tm1Rev/Nr2e1tm1Rev
Tg(CAG-cre/Esr1*)5Amc/?
involves: C57BL/6 * CBA 		abnormal neuron differentiation J:132664
normal behavior/neurological phenotype J:132664
Nr2e1tm1Rev/Nr2e1tm1Rev
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal dentate gyrus morphology J:132664
abnormal short-term spatial reference memory J:132664
abnormal spatial learning J:132664
normal behavior/neurological phenotype J:132664
normal vision/eye phenotype J:132664
Nr2e1tm1Rev/Nr2e1tm1Rtyu
Not Specified 		abnormal neuron differentiation J:132664
Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Not Specified 		abnormal amygdala morphology J:81762
abnormal axon fasciculation J:81762
abnormal eye electrophysiology J:61179
abnormal lateral ganglionic eminence morphology J:81762
abnormal optic nerve morphology J:61179
abnormal optic stalk morphology J:61179
abnormal pallium development J:81762
abnormal retina ganglion layer morphology J:61179
abnormal retina inner nuclear layer morphology J:61179
abnormal retina morphology J:61179
abnormal retina outer nuclear layer morphology J:61179
abnormal retina outer plexiform layer morphology J:61179
abnormal telencephalon development J:81762
absent photoreceptor outer segment J:61179
blindness J:61179
decreased radial glial cell number J:81762
disorganized retina ganglion layer J:61179
disorganized retina inner nuclear layer J:61179
disorganized retina outer nuclear layer J:61179
increased susceptibility to age-related retinal degeneration J:61179
optic nerve degeneration J:61179
Nr2e1tm2Gsc/Nr2e1tm2Gsc
Tg(Camk2a-cre)2Gsc/?
involves: C57BL/6 * FVB/N * SJL 		normal behavior/neurological phenotype J:127237
decreased anxiety-related response J:127237
decreased brain size J:127237
dilated lateral ventricle J:127237
increased aggression towards mice J:127237
postnatal growth retardation J:127237
small hippocampus J:127237
normal vision/eye phenotype J:127237
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory