Myt1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myt1
myelin transcription factor 1
MGI:1100535

11 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myt1^{tm1(EGFP/icre)Ldh}/Myt1^{tm1(EGFP/icre)Ldh} B6.129S-Myt1^{tm1(EGFP/icre)Ldh}	postnatal lethality, complete penetrance	J:169913
Myt1^tm1.1Ggu/Myt1^tm1.1Ggu involves: 129 * C57BL/6 * CBA * CD-1 * SJL	abnormal diaphragm morphology	J:127471
	abnormal PP cell physiology	J:127471
	neonatal lethality, complete penetrance	J:127471
Myt1^tm1Ggu/Myt1^tm1.1Ggu Tg(Pdx1-cre)89.1Dam/? involves: 129 * C57BL/6 * CBA * CD-1 * SJL	abnormal pancreas development	J:127471
	abnormal pancreas secretion	J:127471
	abnormal pancreatic alpha cell physiology	J:127471
	abnormal pancreatic somatostatin secretion	J:127471
	abnormal PP cell physiology	J:127471
	decreased insulin secretion	J:127471
	impaired glucose tolerance	J:127471
Tg(Pdx1-Myt1)2Ggu/0 Not Specified	abnormal pancreatic islet morphology	J:136131

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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