Mid1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mid1
midline 1
MGI:1100537

38 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgap6/Hccs/Mid1^tm1Hzo/Y involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:80528
Arhgap6/Hccs/Mid1^tm1Hzo/Mid1⁺ Tg(EIIa-cre)C5379Lmgd/? involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	prenatal lethality, complete penetrance	J:80528
Arhgap6/Hccs/Mid1^tm1Hzo/Arhgap6/Hccs/Mid1^tm1Hzo involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:80528
Arhgap6/Hccs/Mid1^tm1Hzo/Arhgap6/Hccs/Mid1^tm1Hzo Tg(EIIa-cre)C5379Lmgd/? involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	abnormal embryo development	J:80528
	abnormal gastrulation	J:80528
	embryonic growth retardation	J:80528
	prenatal lethality, complete penetrance	J:80528
Arhgap6/Hccs/Mid1^tm1Hzo/Y Tg(EIIa-cre)C5379Lmgd/? involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	abnormal embryo development	J:80528
	abnormal gastrulation	J:80528
	embryonic growth retardation	J:80528
	prenatal lethality, complete penetrance	J:80528
Mid1^em1(IMPC)Mbp/Mid1⁺ C57BL/6NCrl-Mid1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased total body fat amount	J:211773
	increased freezing behavior	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
	small kidney	J:211773
Mid1^tm1Aash/Mid1^tm1Aash involves: 129	abnormal axon morphology	J:202973
	abnormal corpus callosum morphology	J:202973
	normal embryo phenotype	J:202973
Mid1^tm1Mero/Y B6.Cg-Mid1^tm1Mero	abnormal brain development	J:157828
	abnormal brain morphology	J:157828
	abnormal cerebellar cortex morphology	J:157828
	abnormal cerebellar lobule formation	J:157828
	abnormal cerebellum external granule cell layer morphology	J:157828
	abnormal cerebellum fissure morphology	J:157828
	abnormal cerebellum lobule morphology	J:157828
	abnormal cerebellum vermis lobule I morphology	J:157828
	abnormal cerebellum vermis lobule II morphology	J:157828
	abnormal cerebellum vermis lobule III morphology	J:157828
	abnormal learning/memory/conditioning	J:157828
	abnormal midbrain development	J:157828
	abnormal midbrain-hindbrain boundary development	J:157828
	abnormal midbrain-hindbrain boundary morphology	J:157828
	abnormal motor learning	J:157828
	abnormal tectum morphology	J:157828
	decreased inferior colliculus size	J:157828
	ectopic Purkinje cell	J:157828
	hyperactivity	J:157828
	impaired coordination	J:157828
	impaired limb coordination	J:157828
	increased startle reflex	J:157828
	normal muscle phenotype	J:157828

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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