Kpna4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kpna4
karyopherin subunit alpha 4
MGI:1100848

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kpna4^em1(IMPC)J/Kpna4^em1(IMPC)J C57BL/6NJ-Kpna4^em1(IMPC)J/Mmjax	abnormal vocalization	J:211773
	increased bone mineral density	J:211773
	increased startle reflex	J:211773
Kpna4^tm1Bdr/Kpna4^tm1Bdr B6.Cg-Kpna4^tm1Bdr	increased susceptibility to Orthomyxoviridae infection	J:302003
Kpna4^tm1Maoka/Kpna4^tm1Maoka B6.Cg-Kpna4^tm1Maoka	abnormal sperm axoneme morphology	J:303081
	abnormal sperm flagellum morphology	J:303081
	abnormal sperm head morphology	J:303081
	decreased sperm progressive motility	J:303081
	impaired acrosome reaction	J:303081
	impaired fertilization	J:303081
	reduced male fertility	J:303081

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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