Celsr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
MGI:1100883

63 phenotypes from 8 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Celsr1^Crsh/Celsr1⁺ C3H.Cg-Celsr1^Crsh	delayed neural tube closure	J:216413
Celsr1^Crsh/Celsr1⁺ C3H.Cg-Celsr1^Crsh	head shaking	J:216413
Celsr1^Crsh/Celsr1⁺ involves: 101/H * BALB/c * C3H/HeH	abnormal cochlear sensory epithelium morphology	J:84285
	abnormal orientation of outer hair cell stereociliary bundles	J:84285
	head shaking	J:84285, J:216413
	spinning	J:84285
Celsr1^Crsh/Celsr1^Crsh C3H.Cg-Celsr1^Crsh	abnormal neural plate morphology	J:216413
	craniorachischisis	J:216413
	open neural tube	J:216413
Celsr1^Crsh/Celsr1^Crsh either: (involves: 101/H * C3H/HeH) or (involves: 101/H * BALB/c * C3H/HeH)	abnormal branching involved in lung morphogenesis	J:159690
	abnormal lung epithelium morphology	J:159690
	abnormal lung lobe morphology	J:159690
	abnormal lung morphology	J:159690
	abnormal lung saccule morphology	J:159690
	abnormal respiratory conducting tube morphology	J:159690
	dilated terminal bronchiole tube	J:159690
	impaired branching involved in terminal bronchiole morphogenesis	J:159690
	pulmonary hypoplasia	J:159690
	small lung	J:159690
	small lung lobe	J:159690
	thick lung-associated mesenchyme	J:159690
Celsr1^Crsh/Celsr1^Crsh involves: 101/H * BALB/c * C3H/HeH	abnormal cochlear sensory epithelium morphology	J:84285
	abnormal orientation of outer hair cell stereociliary bundles	J:84285
	abnormal outer hair cell kinocilium location or orientation	J:84285
	absent eyelids	J:84285
	craniorachischisis	J:84285, J:216413
	incomplete rostral neuropore closure	J:84285
	perinatal lethality, complete penetrance	J:84285
Celsr1^Crsh/Celsr1^Scy involves: 101/H * BALB/c * C3H/He * C3H/HeH	craniorachischisis	J:84285
Celsr1^ctb-2J/Celsr1^ctb-2J STOCK Celsr1^ctb-2J/GrsrJ	abnormal coat appearance	J:229303
	circling	J:229303
	curly tail	J:229303
	deafness	J:229303
	decreased body size	J:229303
	head tossing	J:229303
	hydrocephaly	J:229303
	impaired hearing	J:229303
	increased or absent threshold for auditory brainstem response	J:229303
	increased susceptibility to otitis media	J:229303
	prenatal lethality	J:229303
	prenatal lethality, incomplete penetrance	J:229303
	reduced fertility	J:229303
	ruffled hair	J:229303
	testicular atrophy	J:229303
Celsr1^ctb/Celsr1^ctb CByJ.Cg-Celsr1^ctb/GrsrJ	abnormal coat appearance	J:229303
	circling	J:229303
	curly tail	J:229303
	deafness	J:229303
	decreased body size	J:229303
	head tossing	J:229303
	hydrocephaly	J:229303
	impaired hearing	J:229303
	increased or absent threshold for auditory brainstem response	J:229303
	increased susceptibility to otitis media	J:229303
	prenatal lethality, incomplete penetrance	J:229303
	reduced fertility	J:229303
	ruffled hair	J:229303
	testicular atrophy	J:229303
Celsr1^em1(IMPC)Mbp/Celsr1⁺ C57BL/6N-Celsr1^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged testis	J:211773
	increased brain size	J:211773
	no spontaneous movement	J:211773
Celsr1^em1(IMPC)Mbp/Celsr1^em1(IMPC)Mbp C57BL/6N-Celsr1^em1(IMPC)Mbp/MbpMmucd	abnormal tail morphology	J:211773
	female infertility	J:211773
	male infertility	J:211773
	no spontaneous movement	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Celsr1^Scy/Celsr1⁺ involves: BALB/cAnN * C3H/He * C3H/HeH	abnormal cochlear sensory epithelium morphology	J:84285
	abnormal organ of Corti supporting cell morphology	J:84285
	abnormal orientation of outer hair cell stereociliary bundles	J:84285
	cochlear outer hair cell degeneration	J:84285
	head shaking	J:84285
	spinning	J:84285
Celsr1^Scy/Celsr1⁺ involves: BALB/cAnNCrl * C3H/HeN	abnormal involuntary movement	J:63816
Celsr1^Scy/Celsr1⁺ involves: BALB/cAnNCrl * C3H/HeN	head bobbing	J:63816
Celsr1^Scy/Celsr1^Scy involves: BALB/cAnN * C3H/He * C3H/HeH	abnormal cochlear sensory epithelium morphology	J:84285
	abnormal orientation of outer hair cell stereociliary bundles	J:84285
	abnormal outer hair cell kinocilium location or orientation	J:84285
	absent eyelids	J:84285
	craniorachischisis	J:84285
	incomplete rostral neuropore closure	J:84285
	perinatal lethality, complete penetrance	J:84285
Celsr1^tm1.1Fati/Celsr1^tm1.1Fati involves: 129S1/Sv * 129X1/SvJ	abnormal hair follicle orientation	J:157059
	abnormal neural tube closure	J:157059
	cranioschisis	J:157059
	kinked tail	J:157059
	prenatal lethality, incomplete penetrance	J:157059
	whorled hair	J:157059
Celsr1^tm1Fati/Celsr1^tm1Fati Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	whorled hair	J:157059
Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}/Gt(ROSA)26Sor⁺ involves: FVB/N	abnormal anterior visceral endoderm cell migration	J:170681
Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}/Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr} involves: FVB/N	abnormal anterior visceral endoderm cell migration	J:170681

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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