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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prom1
prominin 1
MGI:1100886
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctnnb1tm1Mmt/Ctnnb1+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Prom1tm1(cre/ERT2)Gilb/Prom1+
involves: 129S6/SvEvTac * 129X1/SvJ 		increased intestinal adenocarcinoma incidence J:144215
premature death J:144215
Prom1tm1.1(DTA)Toko/Prom1tm1.1(DTA)Toko
B6.Cg-Prom1tm1.1(DTA)Toko/Rbrc 		decreased retina photoreceptor cell number J:230988
retina photoreceptor degeneration J:230988
thin retina inner nuclear layer J:230988
thin retina inner plexiform layer J:230988
thin retina outer nuclear layer J:230988
thin retina outer plexiform layer J:230988
Prom1tm1.1(DTA)Toko/Prom1tm1.1(DTA)Toko
involves: C57BL/6 * SJL 		no abnormal phenotype detected J:152390
Prom1tm1.1(DTA)Toko/Prom1tm1.1(DTA)Toko
involves: C57BL/6NCrlj * CBA/JNCrlj 		abnormal cone electrophysiology J:230988
abnormal rod electrophysiology J:230988
decreased photoreceptor outer segment number J:230988
decreased retina photoreceptor cell number J:230988
disorganized photoreceptor outer segment J:230988
photoreceptor inner segment degeneration J:230988
photoreceptor outer segment degeneration J:230988
retina outer nuclear layer degeneration J:230988
retina photoreceptor degeneration J:230988
short photoreceptor outer segment J:230988
thin retina outer nuclear layer J:230988
thin retina outer plexiform layer J:230988
Prom1tm1.1(DTA)Toko/Prom1tm1.1(DTA)Toko
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6 * CBA * SJL 		ataxia J:152390
decreased body weight J:152390
increased brain apoptosis J:152390
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory