Tnfrsf9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
MGI:1101059

26 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnfrsf9^em1Ygch/Tnfrsf9^em1Ygch NOD/ShiLtDvs-Tnfrsf9^em1Ygch	abnormal glucose homeostasis	J:208927
	abnormal T cell physiology	J:208927
	normal immune system phenotype	J:208927
	insulitis	J:208927
Tnfrsf9^em2Ygch/Tnfrsf9^em2Ygch NOD/ShiLtDvs-Tnfrsf9^em2Ygch	abnormal glucose homeostasis	J:208927
	abnormal T cell physiology	J:208927
	normal immune system phenotype	J:208927
	insulitis	J:208927
Tnfrsf9^m1Btlr/Tnfrsf9^m1Btlr C57BL/6J-Tnfrsf9^m1Btlr	decreased CD8-positive, alpha-beta T cell number	J:265260
	decreased CD8-positive, naive alpha-beta T cell number	J:265260
	decreased single-positive T cell number	J:265260
	increased B cell number	J:265260
	increased effector memory CD4-positive, alpha-beta T cell number	J:265260
	increased effector memory CD8-positive, alpha-beta T cell number	J:265260
Tnfrsf9^{tm1b(EUCOMM)Wtsi}/Tnfrsf9^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tnfrsf9^{tm1b(EUCOMM)Wtsi}/Ics	preweaning lethality, incomplete penetrance	J:211773
Tnfrsf9^tm1Byk/Tnfrsf9^tm1Byk B6.Cg-Tnfrsf9^tm1Byk	abnormal common myeloid progenitor cell morphology	J:83996
	abnormal cytotoxic T cell physiology	J:83996
	decreased IgG2a level	J:83996
	decreased IgG3 level	J:83996
	decreased interferon-gamma secretion	J:83996
	decreased interleukin-2 secretion	J:83996
	decreased interleukin-4 secretion	J:83996
	increased T cell proliferation	J:83996
Tnfrsf9^tm1Byk/Tnfrsf9^tm1Byk C.Cg-Tnfrsf9^tm1Byk	abnormal common myeloid progenitor cell morphology	J:83996
	abnormal cytotoxic T cell physiology	J:83722
	abnormal immunoglobulin level	J:83996
	decreased IgG2a level	J:83996
	decreased IgG3 level	J:83996
	decreased interferon-gamma secretion	J:83996
	decreased interleukin-2 secretion	J:83996
	decreased interleukin-4 secretion	J:83996
	decreased interleukin-12 secretion	J:83722
	increased IgA level	J:83722
	increased IgG2a level	J:83722
	increased IgG2b level	J:83722
	increased splenocyte proliferation	J:83722
	increased T cell proliferation	J:83996
Tnfrsf9^tm1Lpc/Tnfrsf9^tm1Lpc B6.129-Tnfrsf9^tm1Lpc	abnormal memory T cell physiology	J:145439
Tnfrsf9^tm1Lpc/Tnfrsf9^tm1Lpc B6.129-Tnfrsf9^tm1Lpc	normal immune system phenotype	J:145439

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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