Tnfrsf9 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
MGI:1101059

29 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd28^tm1Pjl/Cd28^tm1Pjl Tnfrsf9^tm1Byk/Tnfrsf9^tm1Byk either: B6.Cg-Cd28^tm1Pjl Tnfrsf9^tm1Byk or C.Cg-Cd28^tm1Pjl Tnfrsf9^tm1Byk	abnormal class switch recombination	J:83722
	abnormal cytotoxic T cell physiology	J:83722
	decreased IgG1 level	J:83722
	decreased IgG2a level	J:83722
	decreased IgM level	J:83722
	decreased interleukin-12 secretion	J:83722
	decreased splenocyte proliferation	J:83722
	decreased susceptibility to type IV hypersensitivity reaction	J:83722
Fas^lpr/Fas^lpr Tnfrsf9^tm1Byk/Tnfrsf9^tm1Byk MRL.Cg-Tnfrsf9^tm1Byk Fas^lpr	abnormal kidney morphology	J:126929
	abnormal lacrimal gland morphology	J:126929
	abnormal outer ear morphology	J:127197
	cortical renal glomerulopathies	J:127197
	enlarged lymph nodes	J:127197
	enlarged spleen	J:127197
	normal hematopoietic system phenotype	J:127197
	increased anti-nuclear antigen antibody level	J:127197
	increased B-1 B cell number	J:127197
	increased B-2 B cell number	J:127197
	increased CD4-positive, alpha-beta T cell number	J:126929, J:127197
	increased double-negative T cell number	J:126929, J:127197
	increased immunoglobulin level	J:127197
	increased interleukin-4 secretion	J:126929
	increased lacrimal gland apoptosis	J:126929
	increased spleen germinal center number	J:127197
	increased susceptibility to systemic lupus erythematosus	J:127197
	lacrimal gland inflammation	J:126929
	premature death	J:127197
	renal glomerular protein deposits	J:127197
	skin lesions	J:127197

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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