Klf10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klf10
Kruppel-like transcription factor 10
MGI:1101353

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Klf10^tm1Sub/Klf10^tm1Sub involves: 129 * C57BL/6	abnormal bone trabecula morphology	J:145678
	abnormal tibia morphology	J:145678
	abnormal trabecular bone morphology	J:145678
	decreased bone mineral content	J:145678
	decreased bone mineral density	J:145678
	decreased bone strength	J:145678
	decreased compact bone thickness	J:145678
	decreased diameter of tibia	J:145678
	decreased femoral compact bone area	J:145678
	decreased osteocyte number	J:145678
	decreased trabecular bone volume	J:145678
Klf10^tm1Sub/Klf10^tm1Sub involves: C57BL/6	abnormal bone ossification	J:95992
Klf10^tm1Sub/Klf10^tm1Sub involves: C57BL/6	increased osteoblast cell number	J:95992
Klf10^tm1Wkle/Klf10^tm1Wkle involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased tumor latency	J:182595
	increased incidence of tumors by chemical induction	J:182595
	increased keratinocyte apoptosis	J:182595
	increased keratinocyte proliferation	J:182595
	increased papilloma incidence	J:182595
	increased tumor growth/size	J:182595

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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