Rnf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf2
ring finger protein 2
MGI:1101759

19 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ Rnf2^tm1Mvi/Rnf2^tm1Mvi involves: 129S/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal neuron differentiation	J:154927
Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a⁺ Rnf2^tm1Mvi/Rnf2^tm1Mvi involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * SJL	abnormal bone marrow cell morphology/development	J:130397
	abnormal common myeloid progenitor cell morphology	J:130397
	decreased B cell number	J:130397
Rnf2^tm1Hko/Rnf2^tm1Hko involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal sternum ossification	J:79851
	cervical vertebral transformation	J:79851
	thoracic vertebral transformation	J:79851
Rnf2^tm1Mvi/Rnf2^tm1Mvi Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * CBA	abnormal B cell differentiation	J:130397
	abnormal bone marrow cell morphology/development	J:130397
	abnormal common myeloid progenitor cell morphology	J:130397
	decreased B cell number	J:130397
	decreased bone marrow cell number	J:130397
	decreased erythrocyte cell number	J:130397
	decreased monocyte cell number	J:130397
	thrombocytosis	J:130397
Rnf2^tm1Mvi/Rnf2^tm1Mvi Tg(Nes-cre/ERT2)5-1Imayo/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal neuron differentiation	J:154927
Rnf2^tm1Mvl/Rnf2^tm1Mvl either: (involves: 129/Ola) or (involves: 129/Ola * FVB)	abnormal embryonic epiblast morphology	J:82399
	abnormal mesoderm development	J:82399
	embryonic growth arrest	J:82399
	embryonic lethality during organogenesis, complete penetrance	J:82399
	failure to gastrulate	J:82399
Rnf2^tm3Hko/Rnf2^tm3Hko involves: 129S1/Sv * 129X1/SvJ	normal reproductive system phenotype	J:204987
Rnf2^tm3Hko/Rnf2^tm3Hko involves: 129S1/Sv * 129X1/SvJ	normal skeleton phenotype	J:204987

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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