Rnf2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf2
ring finger protein 2
MGI:1101759

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmi1^tm1Brn/Bmi1^tm1Brn Rnf2^tm1Mvl/Rnf2⁺ involves: 129/Ola * FVB	abnormal axial skeleton morphology	J:82399
	abnormal cerebellar granule layer morphology	J:82399
	abnormal cerebellar molecular layer	J:82399
	abnormal gait	J:82399
	abnormal Purkinje cell dendrite morphology	J:82399
	decreased body size	J:82399
	decreased body weight	J:82399
	gliosis	J:82399
	impaired coordination	J:82399
	postnatal growth retardation	J:82399
	premature death	J:82399
	small cerebellum	J:82399
Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Rnf2^tm1Mvi/Rnf2^tm1Mvi Tg(Mx1-cre)1Cgn/0 involves: 129 * C57BL/6 * C57BL/10 * CBA * SJL	abnormal common myeloid progenitor cell morphology	J:130397
	enlarged liver	J:130397
	enlarged spleen	J:130397
	normal hematopoietic system phenotype	J:130397
	increased lymphoma incidence	J:130397
	premature death	J:130397
Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Rnf2^tm1Mvl/Rnf2^tm1Mvl involves: 129P2/Ola * 129/Sv * C57BL/6J * FVB/N * SJL	abnormal forebrain development	J:82399
	abnormal somite development	J:82399
	embryonic growth arrest	J:82399
Pcgf2^tm1Hko/Pcgf2^tm1Hko Rnf2^tm1Hko/Rnf2^tm1Hko involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal vertebrae morphology	J:79851
	asymmetric sternocostal joints	J:79851
	normal skeleton phenotype	J:79851

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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