Slc32a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
MGI:1194488

29 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agrp^tm1(cre)Lowl/Agrp⁺ Slc32a1^tm1Lowl/Slc32a1^tm1Lowl involves: 129S6/SvEvTac * C57BL/6	abnormal food intake	J:140858
	abnormal inhibitory postsynaptic currents	J:140858
	decreased body weight	J:140858
	decreased respiratory quotient	J:140858
	decreased susceptibility to diet-induced obesity	J:140858
	decreased total body fat amount	J:140858
	increased locomotor activity	J:140858
	increased oxygen consumption	J:140858
Agrp^tm1(cre)Lowl/Agrp⁺ Slc32a1^tm1Lowl/Slc32a1^tm1Lowl Tg(Pomc1-hrGFP)1Lowl/0 involves: 129S6/SvEvTac * FVB/N	normal nervous system phenotype	J:174691
Slc32a1^tm1.1Bgc/Slc32a1^tm1.1Bgc involves: 129X1/SvJ	abnormal adipose tissue distribution	J:158888
	cleft secondary palate	J:158888
	failure of palatal shelf elevation	J:158888
	hunched posture	J:158888
	perinatal lethality, complete penetrance	J:158888
	respiratory failure	J:158888
	umbilical hernia	J:158888
Slc32a1^tm1Bros/Slc32a1^tm1Bros involves: 129P2/OlaHsd	abnormal inhibitory postsynaptic currents	J:122318
	cleft secondary palate	J:122318
	decreased neurotransmitter release	J:122318
	hunched posture	J:122318
	muscle hypertonia	J:122318
	no spontaneous movement	J:122318
	omphalocele	J:122318
	perinatal lethality, complete penetrance	J:122318
Slc32a1^tm1Yyan/Slc32a1^tm1Yyan Not Specified	abnormal inhibitory postsynaptic potential	J:122055
	abnormal nerve fiber response	J:122055
	abnormal nervous system electrophysiology	J:122055
	cleft palate	J:122055
	neonatal lethality, complete penetrance	J:122055
	omphalocele	J:122055
	primary atelectasis	J:122055
	respiratory failure	J:122055
Slc32a1^tm2(cre)Lowl/Slc32a1⁺ involves: 129S6/SvEvTac	no abnormal phenotype detected	J:174691
Slc32a1^tm2(cre)Lowl/Slc32a1^tm2(cre)Lowl either: B6J.129S6(FVB)-Slc32a1^tm2(cre)Lowl or (involves: 129S6/SvEvTac * C57BL/6J * FVB/N)	abnormal inhibitory postsynaptic currents	J:308516
	increased kindling response	J:308516
	tonic-clonic seizures	J:308516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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