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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tgif1
TGFB-induced factor homeobox 1
MGI:1194497
44 phenotypes from 6 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tgif1tm1.1Caw/Tgif1+
B6.129S-Tgif1tm1.1Caw 		abnormal middle ear morphology J:198238
abnormal placenta intervillous maternal lacunae morphology J:198238
abnormal placenta labyrinth morphology J:198238
hydrocephaly J:198238
impaired hearing J:198238
increased or absent threshold for auditory brainstem response J:198238
increased placenta intervillous maternal lacunae size J:198238
Tgif1tm1.1Caw/Tgif1tm1.1Caw
B6.129S-Tgif1tm1.1Caw 		abnormal cytokine level J:198238
abnormal fluid regulation J:198238
abnormal middle ear morphology J:198238
abnormal pinna reflex J:198238
abnormal placenta intervillous maternal lacunae morphology J:198238
abnormal placenta labyrinth morphology J:198238
abnormal pregnancy J:198238
conductive hearing loss J:198238
deafness J:198238
decreased body size J:198238
hydrocephaly J:198238
impaired hearing J:198238
increased middle ear goblet cell number J:198238
increased or absent threshold for auditory brainstem response J:198238
increased placenta intervillous maternal lacunae size J:198238
increased susceptibility to otitis media J:198238
middle ear effusion J:198238
middle ear polyps J:198238
preweaning lethality, incomplete penetrance J:198238
reduced female fertility J:198238
short face J:198238
short nasal bone J:198238
Tgif1tm1.1Caw/Tgif1tm1.1Caw
involves: C57BL/6 * FVB/N 		no abnormal phenotype detected J:97642
Tgif1tm1Caw/Tgif1tm1Caw
involves: 129S/SvEv * C57BL/6 * FVB/N 		no abnormal phenotype detected J:97642
Tgif1tm1Dwot/Tgif1+
involves: 129X1/SvJ * C57BL/6J 		abnormal response to vitamins J:105576
exencephaly J:105576
Tgif1tm1Dwot/Tgif1tm1Dwot
involves: 129X1/SvJ * C57BL/6J 		abnormal response to vitamins J:105576
exencephaly J:105576
Tgif1tm1Jxd/Tgif1tm1Jxd
either: (involves: 129S/SvEv) or (involves: 129 * C57BL/6) 		no abnormal phenotype detected J:104200
Tgif1tm1Pah/Tgif1tm1Pah
B6.129-Tgif1tm1Pah 		embryonic growth retardation J:109616
Tgif1tm1Pah/Tgif1tm1Pah
involves: 129S/SvEv * CD-1 		abnormal cell cycle J:109616
decreased body size J:109616
decreased cell proliferation J:109616
kinked tail J:109616
situs ambiguus J:109616
situs inversus J:109616
Tgif1tm1Ychn/Tgif1+
involves: 129X1/SvJ * C57BL/6 		abnormal brain development J:117761
abnormal folding of telencephalic vesicles J:117761
abnormal forebrain development J:117761
abnormal hindbrain development J:117761
abnormal midface morphology J:117761
abnormal snout morphology J:117761
abnormal upper lip morphology J:117761
embryonic lethality during organogenesis, incomplete penetrance J:117761
exencephaly J:117761
holoprosencephaly J:117761
microcephaly J:117761
philtrum hypoplasia J:117761
prenatal lethality, incomplete penetrance J:117761
small brain ventricles J:117761
Tgif1tm1Ychn/Tgif1tm1Ychn
involves: 129X1/SvJ * C57BL/6 		abnormal brain development J:117761
exencephaly J:117761
prenatal lethality, incomplete penetrance J:117761
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory