Crx Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crx
cone-rod homeobox
MGI:1194883

58 phenotypes from 10 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crx^{em1(IMPC)Ccpcz}/Crx^{em1(IMPC)Ccpcz} C57BL/6N-Crx^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	decreased exploration in new environment	J:211773
	enlarged heart	J:211773
	enlarged thymus	J:211773
	enlarged urinary bladder	J:211773
	increased fasting circulating glucose level	J:211773
	increased NK cell number	J:211773
	small testis	J:211773
	small thymus	J:211773
Crx^em1Smgc/Crx⁺ C57BL/6J-Crx^em1Smgc	abnormal cone electrophysiology	J:343281
	abnormal retina progenitor cell morphology	J:343281
	abnormal rod electrophysiology	J:343281
	decreased a-wave amplitude	J:343281
	decreased b-wave amplitude	J:343281
	disorganized retina outer nuclear layer	J:343281
	normal vision/eye phenotype	J:343281
Crx^em1Smgc/Crx^em1Smgc C57BL/6J-Crx^em1Smgc	abnormal retina progenitor cell morphology	J:343281
	absent photoreceptor outer segment	J:343281
	absent visual evoked potential	J:343281
	binocular blindness	J:343281
	disorganized retina outer nuclear layer	J:343281
	normal vision/eye phenotype	J:343281
Crx^em2Smgc/Crx⁺ C57BL/6J-Crx^em2Smgc	absent photoreceptor outer segment	J:343281
	absent visual evoked potential	J:343281
	binocular blindness	J:343281
	disorganized retina outer nuclear layer	J:343281
	vision/eye phenotype	J:343281
Crx^em2Smgc/Crx^em2Smgc C57BL/6J-Crx^em2Smgc	absent photoreceptor outer segment	J:343281
	absent visual evoked potential	J:343281
	binocular blindness	J:343281
	disorganized retina outer nuclear layer	J:343281
	vision/eye phenotype	J:343281
Crx^rd23/Crx^rd23 B6.Cg-Crx^rd23/BocJ	abnormal eye electrophysiology	J:348234
	abnormal retina blood vessel morphology	J:348234
	retina degeneration	J:348234
	retina outer nuclear layer degeneration	J:348234
	thin retina outer nuclear layer	J:348234
Crx^Rip/Crx⁺ C57BL/6J-Crx^Rip	abnormal blood circulation	J:203337
	abnormal cone electrophysiology	J:203337
	abnormal retina blood vessel morphology	J:203337
	abnormal retina photoreceptor morphology	J:203337
	abnormal rod electrophysiology	J:203337
	absent photoreceptor outer segment	J:203337
	blindness	J:203337
	retina spots	J:203337
	short photoreceptor inner segment	J:203337
	normal vision/eye phenotype	J:203337
Crx^Rip/Crx^Rip C57BL/6J-Crx^Rip	abnormal retina photoreceptor layer morphology	J:203337
Crx^Rip/Crx^Rip C57BL/6J-Crx^Rip	abnormal retina photoreceptor morphology	J:203337
Crx^tm1.1Smgc/Crx⁺ B6.129X1(CBA)-Crx^tm1.1Smgc	abnormal electroretinogram waveform feature	J:211011
	abnormal retina cone cell morphology	J:211011
	abnormal retina layer morphology	J:211011
	abnormal retina outer nuclear layer morphology	J:211011
	abnormal retina outer nuclear layer thickness	J:211011
	decreased a-wave amplitude	J:211011
	decreased b-wave amplitude	J:211011
	decreased retina cone cell number	J:211011
	short retina rod cell outer segment	J:211011
Crx^tm1.1Smgc/Crx^tm1.1Smgc B6.129X1(CBA)-Crx^tm1.1Smgc	abnormal electroretinogram waveform feature	J:211011
	abnormal retina layer morphology	J:211011
	absent photoreceptor outer segment	J:211011
	retina outer nuclear layer degeneration	J:211011
	normal vision/eye phenotype	J:211011
Crx^tm1Clc/Crx⁺ involves: 129S6/SvEvTac	abnormal photoreceptor outer segment morphology	J:58796
	abnormal retina morphology	J:58796
	thin retina outer nuclear layer	J:58796
Crx^tm1Clc/Crx^tm1Clc involves: 129S6/SvEvTac	abnormal circadian behavior	J:58796
	abnormal cone electrophysiology	J:58796
	abnormal electroretinogram waveform feature	J:211011
	abnormal eye electrophysiology	J:58796
	abnormal photoreceptor inner segment morphology	J:95886
	abnormal photoreceptor outer segment morphology	J:95886
	abnormal retina bipolar cell morphology	J:88825
	abnormal retina cone bipolar cell morphology	J:88825
	abnormal retina horizontal cell morphology	J:88825
	abnormal retina layer morphology	J:211011
	abnormal retina morphology	J:58796
	abnormal retina outer plexiform layer morphology	J:95886
	abnormal retina photoreceptor layer morphology	J:58796
	abnormal retina photoreceptor morphology	J:58796
	abnormal retina rod bipolar cell morphology	J:88825
	abnormal rod electrophysiology	J:58796
	absent photoreceptor outer segment	J:58796, J:211011
	delayed circadian behavior phase	J:58796
	retina outer nuclear layer degeneration	J:211011
	thin retina outer nuclear layer	J:58796, J:88825
	normal vision/eye phenotype	J:211011
Crx^tm1Clc/Crx^tm1Clc involves: 129S6/SvEvTac * C57BL/6J	abnormal retina photoreceptor layer morphology	J:203337
Crx^tm1Smgc/Crx⁺ involves: 129X1/SvJ	abnormal electroretinogram waveform feature	J:211011
	abnormal retina cone cell morphology	J:211011
	short retina rod cell outer segment	J:211011
	normal vision/eye phenotype	J:211011
Crx^tm2.1Smgc/Crx⁺ B6.129X1(CBA)-Crx^tm2.1Smgc	abnormal retina cone cell morphology	J:211011
	decreased b-wave amplitude	J:211011
	normal vision/eye phenotype	J:211011
Crx^tm2.1Smgc/Crx^tm2.1Smgc B6.129X1(CBA)-Crx^tm2.1Smgc	abnormal electroretinogram waveform feature	J:211011
	abnormal retina layer morphology	J:211011
	absent photoreceptor outer segment	J:211011
	retina outer nuclear layer degeneration	J:211011
	normal vision/eye phenotype	J:211011
Crx^tvrm65/Crx^tvrm65 C57BL/6J-Crx^tvrm65/J	abnormal ocular fundus morphology	J:166679
	abnormal retina pigmentation	J:166679
	absent photoreceptor inner segment	J:166679
	absent photoreceptor outer segment	J:166679
	retina outer nuclear layer degeneration	J:166679
	retina photoreceptor degeneration	J:166679
	thin retina outer plexiform layer	J:166679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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