Ttk Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ttk
Ttk protein kinase
MGI:1194921

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Zp3-cre)93Knw/0 Ttk^tm1Katj/Ttk^tm1Katj involves: 129 * C57BL/6 * C57BL/6J	abnormal female meiosis	J:173618
	abnormal meiotic spindle assembly checkpoint	J:173618
	aneuploidy	J:173618
	decreased litter size	J:173618
	enhanced polar body extrusion	J:173618
	reduced female fertility	J:173618
Ttk^em1(IMPC)J/Ttk⁺ C57BL/6NJ-Ttk^em1(IMPC)J/Mmjax	decreased leukocyte cell number	J:211773
Ttk^em1(IMPC)J/Ttk^em1(IMPC)J C57BL/6NJ-Ttk^em1(IMPC)J/Mmjax	abnormal embryo implantation	J:279207
	abnormal inner cell mass morphology	J:279207
	embryonic lethality between implantation and somite formation, complete penetrance	J:279207
	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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