Per2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Per2
period circadian clock 2
MGI:1195265

49 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Per2^M1Btlr/Per2⁺ C57BL/6J-Per2^M1Btlr	shortened circadian behavior period	J:101977
Per2^M1Btlr/Per2^M1Btlr C57BL/6J-Per2^M1Btlr	abnormal brain wave pattern	J:101977
	abnormal circadian behavior	J:264638
	delayed circadian behavior phase	J:264638
	shortened circadian behavior period	J:101977
Per2^{tm1a(EUCOMM)Hmgu}/Per2^{tm1a(EUCOMM)Hmgu} C57BL/6N-Per2^{tm1a(EUCOMM)Hmgu}/H	abnormal bone mineralization	J:165965
	abnormal coat/hair pigmentation	J:165965
	increased circulating alkaline phosphatase level	J:165965
Per2^tm1Brd/Per2^tm1Brd involves: 129S7/SvEvBrd * C57BL/6	abnormal basal metabolism	J:136165
	abnormal body weight	J:136165
	abnormal circadian sleep/wake cycle	J:89417
	abnormal food intake	J:136165
	abnormal food preference	J:136165
	abnormal locomotor circadian rhythm	J:56167
	abnormal male preputial gland morphology	J:79456
	abnormal maternal behavior	J:136165
	abnormal pregnancy	J:136165
	absent estrous cycle	J:136165
	arrhythmic circadian behavior persistence	J:56167
	normal behavior/neurological phenotype	J:56167, J:77340
	decreased cellular sensitivity to gamma-irradiation	J:79456
	decreased litter size	J:136165
	early reproductive senescence	J:136165
	enhanced behavioral response to cocaine	J:77340
	enhanced conditioned place preference behavior	J:77340
	increased body weight	J:136165
	increased bone ossification	J:163112
	increased bone volume	J:163112
	increased incidence of tumors by ionizing radiation induction	J:79456
	increased lymphoma incidence	J:79456
	increased mortality induced by gamma-irradiation	J:79456
	normal nervous system phenotype	J:56167
	premature death	J:79456
	prolonged estrous cycle	J:136165
	pup cannibalization	J:136165
	reduced female fertility	J:136165
	salivary gland epithelial hyperplasia	J:79456
	shortened circadian behavior period	J:56167
Per2^tm1Ccl/Per2^tm1Ccl involves: 129 * C57BL/6	arrhythmic circadian behavior persistence	J:79456
	decreased cellular sensitivity to gamma-irradiation	J:79456
	increased salivary gland tumor incidence	J:79456
	salivary gland epithelial hyperplasia	J:79456
	shortened circadian behavior period	J:79456
Per2^tm1Drw/Per2^tm1Drw B6.129-Per2^tm1Drw/J	abnormal blood vessel morphology	J:208598
	abnormal bone marrow cell morphology/development	J:208598
	abnormal hematopoietic stem cell physiology	J:208598
	abnormal nervous system morphology	J:208598
	abnormal retina morphology	J:208598
	abnormal retina vasculature morphology	J:208598
	decreased hematopoietic stem cell proliferation	J:208598
	improved glucose tolerance	J:208598
	increased hematopoietic stem cell number	J:208598
Per2^tm1Drw/Per2^tm1Drw involves: 129	abnormal circadian temperature homeostasis	J:95746
	abnormal sleep pattern	J:95746
	arrhythmic circadian behavior persistence	J:69626
Per2^tm1Jt/Per2^tm1Jt involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:89256

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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