Per2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Per2
period circadian clock 2
MGI:1195265

26 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Per2^tm1Jt/Per2⁺ Smg6^tm1.1Tac/Smg6^tm1.1Tac involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J	abnormal circadian behavior phase	J:342742
	abnormal circardian behavior entrainment	J:342742
	abnormal locomotor circadian rhythm	J:342742
	prolonged circadian behavior period	J:342742
Clock^m1Jt/Clock⁺ Per2^tm1Jt/Per2⁺ Usf1^soc/? involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J	abnormal circadian behavior period	J:198519
Cry1^tm1Jhjh/Cry1^tm1Jhjh Per2^tm1Brd/Per2^tm1Brd involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	arrhythmic circadian behavior persistence	J:79492
Cry2^tm1.1Yf/Cry2^tm1.1Yf Per2^tm1Jt/Per2^tm1Jt B6J.Cg-Cry2^tm1.1Yf Per2^tm1Jt	abnormal liver physiology	J:224319
Cry2^tm1Jhjh/Cry2^tm1Jhjh Per2^tm1Brd/Per2^tm1Brd involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	normal behavior/neurological phenotype	J:79492
	decreased bone ossification	J:163112
	decreased osteoblast cell number	J:163112
Opn1sw^tm1.2Mnei/Opn1sw^tm1.2Mnei Per2^tm1Jt/Per2⁺ involves: 129S6/SvEvTac	normal vision/eye phenotype	J:227078
Opn3^{tm2b(EUCOMM)Wtsi}/Opn3^{tm2b(EUCOMM)Wtsi} Per2^tm1Jt/Per2⁺ involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * CBA	normal behavior/neurological phenotype	J:227078
Opn5^tm1.1Lan/Opn5^tm1.1Lan Per2^tm1Jt/Per2⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6N * FVB/N	abnormal eye physiology	J:227078
Opn5^tm1.1Lan/Opn5^tm1.1Yau Per2^tm1Jt/Per2⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6N * FVB/N	abnormal eye physiology	J:227078
Opn5^tm1.1Yau/Opn5^tm1.1Yau Per2^tm1Jt/Per2⁺ involves: 129S6/SvEvTac	abnormal eye physiology	J:227078
	normal vision/eye phenotype	J:227078
Per1^tm1Brd/Per1^tm1Brd Per2^tm1Brd/Per2^tm1.1Kry Tg(Col1a1-cre)1Kry/0 involves: 129S7/SvEvBrd * FVB	abnormal skeleton development	J:115188
	increased bone mass	J:115188
	increased osteoblast cell number	J:115188
Per1^tm1Brd/Per1^tm1Brd Per2^tm1Brd/Per2^tm1Brd involves: 129S7/SvEvBrd	abnormal bone marrow cell morphology/development	J:115188
	abnormal fibroblast physiology	J:193286
	abnormal skeleton development	J:115188
	abnormal urine catecholamine level	J:115188
	impaired wound healing	J:193286
	increased bone mass	J:115188
	increased circulating leptin level	J:115188
	increased osteoblast cell number	J:115188
	increased osteoblast proliferation	J:115188
Per1^tm1Brd/Per1^tm1Brd Per2^tm1Brd/Per2^tm1Brd involves: 129S7/SvEvBrd * C57BL/6	arrhythmic circadian behavior persistence	J:69769
Per1^tm1Drw/Per1^tm1Drw Per2^tm1Drw/Per2^tm1Drw involves: 129S4/SvJae	abnormal brain wave pattern	J:95746
	abnormal circadian temperature homeostasis	J:95746
	abnormal sleep pattern	J:95746
	arrhythmic circadian behavior persistence	J:69626, J:95746
Per2^tm1Drw/Per2^tm1Drw Per3^tm1Drw/Per3^tm1Drw involves: 129/Sv * 129S4/SvJae	arrhythmic circadian behavior persistence	J:69626
Per2^tm1Drw/Per2^tm1Drw Tg(PER2*S662D)382Ljp/0 involves: C57BL/6	prolonged circadian behavior period	J:126404
Per2^tm1Drw/Per2^tm1Drw Tg(PER2*S662G)867Ljp/0 involves: C57BL/6	shortened circadian behavior period	J:126404
Per2^tm1Jt/Per2⁺ Zfhx3^Sci/Zfhx3⁺ involves: 129S6/SvEvTac * BALB/cOlaHsd * C3H/HeH * C57BL/6J	abnormal hypothalamus physiology	J:223990

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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