Cd70 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd70
CD70 antigen
MGI:1195273

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd70^tm1(cre)Jbo/Cd70^tm1(cre)Jbo B6.129P2-Cd70^tm1(cre)Jbo	decreased regulatory T cell number	J:198200
Cd70^tm1(cre)Jbo/Cd70^tm1(cre)Jbo B6.129P2-Cd70^tm1(cre)Jbo	normal immune system phenotype	J:198200
Cd70^tm1.1Jda/Cd70^tm1.1Jda B6.Cg-Cd70^tm1.1Jda	abnormal CD8-positive, alpha-beta T cell physiology	J:193042
	abnormal immune system physiology	J:193042
	abnormal T cell physiology	J:193042
	decreased CD8-positive, alpha-beta T cell number	J:193042
	normal immune system phenotype	J:193042
	increased susceptibility to Riboviria infection	J:193042
Tg(CD19-Tnfsf7)#Rvl/0 involves: C57BL/6	abnormal metallophilic macrophage morphology	J:88620
	abnormal spleen marginal zone macrophage morphology	J:88620
	abnormal spleen marginal zone morphology	J:88620
	decreased B cell number	J:88620
	decreased mature B cell number	J:88620
	decreased transitional stage B cell number	J:88620

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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